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Preclinical evidence for an effective therapeutic activity of FL118, a novel survivin inhibitor, in patients with relapsed/refractory multiple myeloma.
Holthof, Lisa C; van der Horst, Hilma J; van Hal-van Veen, Susan E; Ruiter, Ruud W J; Li, Fengzhi; Buijze, Marijke; Andersen, Morten N; Yuan, Huipin; de Bruijn, Joost; van de Donk, Niels W C J; Lokhorst, Henk M; Zweegman, Sonja; Groen, Richard W J; Mutis, Tuna.
Afiliação
  • Holthof LC; Department of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands.
  • van der Horst HJ; Department of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands.
  • van Hal-van Veen SE; Department of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands.
  • Ruiter RWJ; Department of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands.
  • Li F; Department of Pharmacology & Therapeutics, Roswell Park Comprehensive Cancer Center, New York, NJ USA.
  • Buijze M; Department of Otolaryngology-Head and Neck Surgery, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands.
  • Andersen MN; Department of Clinical Biochemistry, Aarhus University Hospital, Aarhus, Denmark.
  • Yuan H; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • de Bruijn J; Department of Hematology, Aarhus University Hospital, Aarhus, Denmark.
  • van de Donk NWCJ; Kuros Biosciences BV, Bilthoven, the Netherlands.
  • Lokhorst HM; Kuros Biosciences BV, Bilthoven, the Netherlands.
  • Zweegman S; The School of Engineering and Materials Science, Queen Mary University of London, London, UK.
  • Groen RWJ; Department of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands.
  • Mutis T; Department of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands.
Haematologica ; 105(2): e80-e83, 2020.
Article em En | MEDLINE | ID: mdl-31123033
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Survivina / Indolizinas / Mieloma Múltiplo Limite: Humans Idioma: En Revista: Haematologica Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda País de publicação: Itália
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Survivina / Indolizinas / Mieloma Múltiplo Limite: Humans Idioma: En Revista: Haematologica Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda País de publicação: Itália