Pharmacophore studies of 1, 3, 4-oxadiazole nucleus: Lead compounds as &#945;-glucosidase inhibitors.

Khan, Haroon; Zafar, Muhammad; Patel, Seema; Shah, Sm Mukarrum; Bishayee, Anupam

Pharmacophore studies of 1, 3, 4-oxadiazole nucleus: Lead compounds as α-glucosidase inhibitors.

Khan, Haroon; Zafar, Muhammad; Patel, Seema; Shah, Sm Mukarrum; Bishayee, Anupam.

Afiliação

Khan H; Department of Pharmacy, Abdul Wali Khan University Mardan, 23200, Pakistan. Electronic address: hkdr2006@gmail.com.
Zafar M; Department of Pharmacy, Abdul Wali Khan University Mardan, 23200, Pakistan.
Patel S; Bioinformatics and Medical Informatics Research Center, San Diego State University, San Diego, 92182, USA.
Shah SM; Department of Pharmacy, University of Swabi, Pakistan.
Bishayee A; Lake Erie College of Osteopathic Medicine, Bradenton, FL, 34211, USA.

Food Chem Toxicol ; 130: 207-218, 2019 Aug.

Article em En | MEDLINE | ID: mdl-31128218

Assuntos

Oxidiazóis/química; Oxidiazóis/farmacologia; alfa-Glucosidases/metabolismo; Descoberta de Drogas; Inibidores de Glicosídeo Hidrolases/farmacologia; Simulação de Acoplamento Molecular; Estrutura Molecular; Relação Estrutura-Atividade; alfa-Glucosidases/genética

Palavras-chave

Molecular docking; Pharmacophore modeling; Pharmacophore-based virtual screening; α-glucosidase enzyme

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxidiazóis / Alfa-Glucosidases Idioma: En Revista: Food Chem Toxicol Ano de publicação: 2019 Tipo de documento: Article País de publicação: Reino Unido

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google