A naphthalimide-aminal-based pH-sensitive fluorescent donor for lysosome-targeted formaldehyde release and fluorescence turn-on readout.

Xu, Hang; Ma, Shengnan; Liu, Qianqian; Huang, Lixian; Wu, Peimin; Liu, Xiaolin; Huang, Yali; Wang, Xiaolei; Xu, Huan; Lou, Kaiyan; Wang, Wei

Xu, Hang; Ma, Shengnan; Liu, Qianqian; Huang, Lixian; Wu, Peimin; Liu, Xiaolin; Huang, Yali; Wang, Xiaolei; Xu, Huan; Lou, Kaiyan; Wang, Wei.

Afiliação

Xu H; State Key Laboratory of Bioengineering Reactor, Shanghai Key Laboratory of New Drug Design, and Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science & Technology, 130 Meilong Road, Shanghai 200237, China. xuhuan@ecust.edu.cn kylou@ecust.edu.cn.
Ma S; State Key Laboratory of Bioengineering Reactor, Shanghai Key Laboratory of New Drug Design, and Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science & Technology, 130 Meilong Road, Shanghai 200237, China. xuhuan@ecust.edu.cn kylou@ecust.edu.cn.
Liu Q; State Key Laboratory of Bioengineering Reactor, Shanghai Key Laboratory of New Drug Design, and Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science & Technology, 130 Meilong Road, Shanghai 200237, China. xuhuan@ecust.edu.cn kylou@ecust.edu.cn.
Huang L; State Key Laboratory of Bioengineering Reactor, Shanghai Key Laboratory of New Drug Design, and Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science & Technology, 130 Meilong Road, Shanghai 200237, China. xuhuan@ecust.edu.cn kylou@ecust.edu.cn.
Wu P; State Key Laboratory of Bioengineering Reactor, Shanghai Key Laboratory of New Drug Design, and Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science & Technology, 130 Meilong Road, Shanghai 200237, China. xuhuan@ecust.edu.cn kylou@ecust.edu.cn.
Liu X; State Key Laboratory of Bioengineering Reactor, Shanghai Key Laboratory of New Drug Design, and Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science & Technology, 130 Meilong Road, Shanghai 200237, China. xuhuan@ecust.edu.cn kylou@ecust.edu.cn.
Huang Y; State Key Laboratory of Bioengineering Reactor, Shanghai Key Laboratory of New Drug Design, and Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science & Technology, 130 Meilong Road, Shanghai 200237, China. xuhuan@ecust.edu.cn kylou@ecust.edu.cn.
Wang X; State Key Laboratory of Bioengineering Reactor, Shanghai Key Laboratory of New Drug Design, and Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science & Technology, 130 Meilong Road, Shanghai 200237, China. xuhuan@ecust.edu.cn kylou@ecust.edu.cn.
Xu H; State Key Laboratory of Bioengineering Reactor, Shanghai Key Laboratory of New Drug Design, and Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science & Technology, 130 Meilong Road, Shanghai 200237, China. xuhuan@ecust.edu.cn kylou@ecust.edu.cn.
Lou K; State Key Laboratory of Bioengineering Reactor, Shanghai Key Laboratory of New Drug Design, and Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science & Technology, 130 Meilong Road, Shanghai 200237, China. xuhuan@ecust.edu.cn kylou@ecust.edu.cn.
Wang W; State Key Laboratory of Bioengineering Reactor, Shanghai Key Laboratory of New Drug Design, and Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science & Technology, 130 Meilong Road, Shanghai 200237, China. xuhuan@ecust.edu.cn kylou@ecust.edu.cn and Dep

Chem Commun (Camb) ; 55(49): 7053-7056, 2019 Jun 21.

Article em En | MEDLINE | ID: mdl-31143885

Assuntos

Fluorescência; Corantes Fluorescentes/química; Formaldeído/metabolismo; Lisossomos/metabolismo; Naftalimidas/química; Imagem Óptica; Formaldeído/química; Células HeLa; Humanos; Concentração de Íons de Hidrogênio; Lisossomos/química; Estrutura Molecular

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Naftalimidas / Imagem Óptica / Fluorescência / Corantes Fluorescentes / Formaldeído / Lisossomos Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Chem Commun (Camb) Assunto da revista: QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de publicação: Reino Unido

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