Dopamine synthesis in rat striatum: mobilization of tyrosine from non-dopaminergic cells.
Experientia
; 43(10): 1109-10, 1987 Oct 15.
Article
em En
| MEDLINE
| ID: mdl-3117583
ABSTRACT
Unilateral nigrostriatal lesions in rats that almost totally depleted striatal dopamine had no effect on striatal levels of dopamine's precursor, tyrosine, nor on those of leucine. Since prolonged electrical stimulation of the slices markedly depletes them of tyrosine (1,2) we conclude that tyrosine can be mobilized from non-dopaminergic striatal cells to augment dopamine release.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tirosina
/
Dopamina
/
Corpo Estriado
Limite:
Animals
Idioma:
En
Revista:
Experientia
Ano de publicação:
1987
Tipo de documento:
Article