Does kisspeptin participate in GABA-mediated modulation of GnRH and GnRH receptor biosynthesis in the hypothalamic-pituitary unit of follicular-phase ewes?

Ciechanowska, Magdalena Olga; Lapot, Magdalena; Kowalczyk, Marek; Malewski, Tadeusz; Brytan, Marek; Antkowiak, Bozena; Przekop, Franciszek

Ciechanowska, Magdalena Olga; Lapot, Magdalena; Kowalczyk, Marek; Malewski, Tadeusz; Brytan, Marek; Antkowiak, Bozena; Przekop, Franciszek.

Afiliação

Ciechanowska MO; The General Karol Kaczkowski Military Institute of Hygiene and Epidemiology, Department of Pharmacology and Toxicology, Warszawa, Poland. Electronic address: mciechanowska@wihe.waw.pl.
Lapot M; The General Karol Kaczkowski Military Institute of Hygiene and Epidemiology, Department of Pharmacology and Toxicology, Warszawa, Poland.
Kowalczyk M; The Józef Pilsudski University of Physical Education, Warszawa, Poland.
Malewski T; The Museum and Institute of Zoology, Polish Academy of Sciences, Warszawa, Poland.
Brytan M; The General Karol Kaczkowski Military Institute of Hygiene and Epidemiology, Department of Pharmacology and Toxicology, Warszawa, Poland.
Antkowiak B; The General Karol Kaczkowski Military Institute of Hygiene and Epidemiology, Department of Pharmacology and Toxicology, Warszawa, Poland.
Przekop F; The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Department of Neuroendocrinology, Warszawa, Poland.

Pharmacol Rep ; 71(4): 636-643, 2019 Aug.

Article em En | MEDLINE | ID: mdl-31176893

Assuntos

Ciclo Estral/metabolismo; Hormônio Liberador de Gonadotropina/biossíntese; Sistema Hipotálamo-Hipofisário/efeitos dos fármacos; Kisspeptinas/metabolismo; Receptores de GABA-A/metabolismo; Receptores LHRH/biossíntese; Animais; Bicuculina/farmacologia; Feminino; Agonistas de Receptores de GABA-A/farmacologia; Antagonistas de Receptores de GABA-A/farmacologia; Hormônio Liberador de Gonadotropina/sangue; Sistema Hipotálamo-Hipofisário/metabolismo; Muscimol/farmacologia; Neurônios/metabolismo; Ovinos

Palavras-chave

Ewe; GABA(A)R; GnRH/GnRHR; Hypothalamus; Kiss1

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hormônio Liberador de Gonadotropina / Receptores de GABA-A / Receptores LHRH / Ciclo Estral / Kisspeptinas / Sistema Hipotálamo-Hipofisário Limite: Animals Idioma: En Revista: Pharmacol Rep Assunto da revista: FARMACOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de publicação: Suíça

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