Neurolastin, a dynamin family GTPase, translocates to mitochondria upon neuronal stress and alters mitochondrial morphology <i>in vivo</i>.

Lomash, Richa Madan; Petralia, Ronald S; Holtzclaw, Lynne A; Tsuda, Mumeko C; Wang, Ya-Xian; Badger, John D; Cameron, Heather A; Youle, Richard J; Roche, Katherine W

Neurolastin, a dynamin family GTPase, translocates to mitochondria upon neuronal stress and alters mitochondrial morphology in vivo.

Lomash, Richa Madan; Petralia, Ronald S; Holtzclaw, Lynne A; Tsuda, Mumeko C; Wang, Ya-Xian; Badger, John D; Cameron, Heather A; Youle, Richard J; Roche, Katherine W.

Afiliação

Lomash RM; Receptor Biology Section, NINDS, National Institutes of Health, Bethesda, Maryland 20892 richa.madanlomash@nih.gov.
Petralia RS; Advanced Imaging Core, NIDCD, National Institutes of Health, Bethesda, Maryland 20892.
Holtzclaw LA; Microscopy and Imaging Core, NICHD, National Institutes of Health, Bethesda, Maryland 20892.
Tsuda MC; Section on Neuroplasticity, NIMH, National Institutes of Health, Bethesda, Maryland 20892.
Wang YX; Advanced Imaging Core, NIDCD, National Institutes of Health, Bethesda, Maryland 20892.
Badger JD; Receptor Biology Section, NINDS, National Institutes of Health, Bethesda, Maryland 20892.
Cameron HA; Section on Neuroplasticity, NIMH, National Institutes of Health, Bethesda, Maryland 20892.
Youle RJ; Surgical Neurology Branch, NINDS, National Institutes of Health, Bethesda, Maryland 20892.
Roche KW; Receptor Biology Section, NINDS, National Institutes of Health, Bethesda, Maryland 20892 rochek@ninds.nih.gov.

J Biol Chem ; 294(30): 11498-11512, 2019 07 26.

Article em En | MEDLINE | ID: mdl-31177092

Assuntos

Dinaminas/metabolismo; Mitocôndrias/metabolismo; Células de Purkinje/metabolismo; Animais; Células Cultivadas; Dinaminas/genética; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Mitocôndrias/enzimologia; Mutação; Transporte Proteico

Palavras-chave

E3 ubiquitin ligase; GTPase; brain; dynamin; mechanoenzyme; membrane fusion; membrane remodeling; mitochondria; neurotransmission; organellar morphology; synaptic transmission

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células de Purkinje / Dinaminas / Mitocôndrias Limite: Animals Idioma: En Revista: J Biol Chem Ano de publicação: 2019 Tipo de documento: Article País de publicação: Estados Unidos

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google