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Feedback Activation of SGK3 and AKT Contributes to Rapamycin Resistance by Reactivating mTORC1/4EBP1 Axis via TSC2 in Breast Cancer.
Wang, Hongtao; Huang, Fang; Zhang, Zhe; Wang, Peng; Luo, Yuan; Li, Hailiang; Li, Na; Wang, Jian; Zhou, Jianguang; Wang, Yongan; Li, Shanhu.
Afiliação
  • Wang H; Department of Cell Engineering, Beijing Institute of Biotechnology, Beijing 100850, China.
  • Huang F; State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300200, China.
  • Zhang Z; Department of Cell Engineering, Beijing Institute of Biotechnology, Beijing 100850, China.
  • Wang P; Department of Cell Engineering, Beijing Institute of Biotechnology, Beijing 100850, China.
  • Luo Y; Department of Cell Engineering, Beijing Institute of Biotechnology, Beijing 100850, China.
  • Li H; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
  • Li N; Zhuhai People's Hospital, Zhuhai Hospital Affiliated Jinan University, Zhuhai 519000, China.
  • Wang J; Department of Cell Engineering, Beijing Institute of Biotechnology, Beijing 100850, China.
  • Zhou J; Department of Cell Engineering, Beijing Institute of Biotechnology, Beijing 100850, China.
  • Wang Y; Department of Cell Engineering, Beijing Institute of Biotechnology, Beijing 100850, China.
  • Li S; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
Int J Biol Sci ; 15(5): 929-941, 2019.
Article em En | MEDLINE | ID: mdl-31182914

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Proteínas Serina-Treonina Quinases / Sirolimo / Proteínas Proto-Oncogênicas c-akt / Alvo Mecanístico do Complexo 1 de Rapamicina Limite: Humans Idioma: En Revista: Int J Biol Sci Assunto da revista: BIOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Austrália

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Proteínas Serina-Treonina Quinases / Sirolimo / Proteínas Proto-Oncogênicas c-akt / Alvo Mecanístico do Complexo 1 de Rapamicina Limite: Humans Idioma: En Revista: Int J Biol Sci Assunto da revista: BIOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Austrália