Subgroup-specific prognostic signaling and metabolic pathways in pediatric medulloblastoma.

Park, Ae Kyung; Lee, Ji Yeoun; Cheong, Heesun; Ramaswamy, Vijay; Park, Sung-Hye; Kool, Marcel; Phi, Ji Hoon; Choi, Seung Ah; Cavalli, Florence; Taylor, Michael D; Kim, Seung-Ki

Park, Ae Kyung; Lee, Ji Yeoun; Cheong, Heesun; Ramaswamy, Vijay; Park, Sung-Hye; Kool, Marcel; Phi, Ji Hoon; Choi, Seung Ah; Cavalli, Florence; Taylor, Michael D; Kim, Seung-Ki.

Afiliação

Park AK; College of Pharmacy and Research Institute of Life and Pharmaceutical Sciences, Sunchon National University, Suncheon, Korea.
Lee JY; Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea.
Cheong H; Department of Anatomy, Neural Development and Anomaly Lab, Seoul National University College of Medicine, Seoul, Korea.
Ramaswamy V; Neuroscience Research Institute, Seoul National University College of Medicine, Seoul, Korea.
Park SH; Division of Cancer Biology, National Cancer Center, Goyang, Korea.
Kool M; Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, Canada.
Phi JH; Department of Pathology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Choi SA; Division of Paediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Cavalli F; Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea.
Taylor MD; Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea.
Kim SK; Programme in Developmental and Stem Cell Biology, Hospital for Sick Children, Toronto, Canada.

BMC Cancer ; 19(1): 571, 2019 Jun 11.

Article em En | MEDLINE | ID: mdl-31185958

Assuntos

Neoplasias Cerebelares/genética; Neoplasias Cerebelares/metabolismo; Meduloblastoma/genética; Meduloblastoma/metabolismo; Redes e Vias Metabólicas; Biomarcadores Tumorais/genética; Biomarcadores Tumorais/metabolismo; Neoplasias Cerebelares/diagnóstico; Criança; Saúde da Criança; Pré-Escolar; Feminino; Proteína Forkhead Box M1/genética; Proteína Forkhead Box M1/metabolismo; Expressão Gênica; Proteínas Hedgehog/genética; Proteínas Hedgehog/metabolismo; Humanos; Inflamação/metabolismo; Estimativa de Kaplan-Meier; Masculino; Meduloblastoma/diagnóstico; Prognóstico; Modelos de Riscos Proporcionais; Receptores Proteína Tirosina Quinases/genética; Receptores Proteína Tirosina Quinases/metabolismo; Transdução de Sinais/genética; Proteína GLI1 em Dedos de Zinco/genética; Proteína GLI1 em Dedos de Zinco/metabolismo

Palavras-chave

Medulloblastoma; Metabolic pathway; Prognosis; Signaling pathway; Subgroup; Targeted therapy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cerebelares / Redes e Vias Metabólicas / Meduloblastoma Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Child / Child, preschool / Female / Humans / Male Idioma: En Revista: BMC Cancer Assunto da revista: NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article País de publicação: Reino Unido

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