LW6 enhances chemosensitivity to gemcitabine and inhibits autophagic flux in pancreatic cancer.

Zhang, Xianbin; Kumstel, Simone; Jiang, Ke; Meng, Songshu; Gong, Peng; Vollmar, Brigitte; Zechner, Dietmar

Zhang, Xianbin; Kumstel, Simone; Jiang, Ke; Meng, Songshu; Gong, Peng; Vollmar, Brigitte; Zechner, Dietmar.

Afiliação

Zhang X; Institute for Experimental Surgery, Rostock University Medical Center, Schillingallee 69a, 18059 Rostock, Germany.
Kumstel S; Institute for Experimental Surgery, Rostock University Medical Center, Schillingallee 69a, 18059 Rostock, Germany.
Jiang K; Cancer Center, Institute of Cancer Stem Cell, Dalian Medical University, Lvshun South Road 9W, 116044 Dalian, China.
Meng S; Cancer Center, Institute of Cancer Stem Cell, Dalian Medical University, Lvshun South Road 9W, 116044 Dalian, China.
Gong P; Department of General Surgery, Shenzhen University General Hospital, Xueyuan Road 1098, 518055 Shenzhen, China.
Vollmar B; Institute for Experimental Surgery, Rostock University Medical Center, Schillingallee 69a, 18059 Rostock, Germany.
Zechner D; Institute for Experimental Surgery, Rostock University Medical Center, Schillingallee 69a, 18059 Rostock, Germany.

J Adv Res ; 20: 9-21, 2019 Nov.

Article em En | MEDLINE | ID: mdl-31193017

Palavras-chave

3-MA, 3-methyladenine; ATCC, American Type Culture Collection; Autophagy; BrdU, 5-bromo-2'-deoxyuridine; CQ, chloroquine; Combination therapy; Gemcitabine; LC3, microtubule-associated protein 1 light chain 3; LW6; Pancreatic cancer; p62, p62/SQSTM1

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: J Adv Res Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Egito

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