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Modeling microcephaly with cerebral organoids reveals a WDR62-CEP170-KIF2A pathway promoting cilium disassembly in neural progenitors.
Zhang, Wei; Yang, Si-Lu; Yang, Mei; Herrlinger, Stephanie; Shao, Qiang; Collar, John L; Fierro, Edgar; Shi, Yanhong; Liu, Aimin; Lu, Hui; Herring, Bruce E; Guo, Ming-Lei; Buch, Shilpa; Zhao, Zhen; Xu, Jian; Lu, Zhipeng; Chen, Jian-Fu.
Afiliação
  • Zhang W; Center for Craniofacial Molecular Biology, University of Southern California (USC), Los Angeles, CA, 90033, USA.
  • Yang SL; Department of Genetics, University of Georgia, Athens, GA, 30602, USA.
  • Yang M; Center for Craniofacial Molecular Biology, University of Southern California (USC), Los Angeles, CA, 90033, USA.
  • Herrlinger S; Department of Genetics, University of Georgia, Athens, GA, 30602, USA.
  • Shao Q; Center for Craniofacial Molecular Biology, University of Southern California (USC), Los Angeles, CA, 90033, USA.
  • Collar JL; Department of Genetics, University of Georgia, Athens, GA, 30602, USA.
  • Fierro E; Department of Genetics, University of Georgia, Athens, GA, 30602, USA.
  • Shi Y; Division of Stem Cell Biology Research, Department of Developmental and Stem Cell Biology, Beckman Research Institute of City of Hope, Duarte, CA, 91010, USA.
  • Liu A; Department of Biology, Eberly College of Science, The Pennsylvania State University, University Park, PA, 16802, USA.
  • Lu H; Department of Pharmacology and Physiology, The George Washington University, Washington, DC, 20037, USA.
  • Herring BE; Department of Biological Sciences, University of Southern California, Los Angeles, CA, 90089, USA.
  • Guo ML; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
  • Buch S; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
  • Zhao Z; Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA.
  • Xu J; Center for Craniofacial Molecular Biology, University of Southern California (USC), Los Angeles, CA, 90033, USA.
  • Lu Z; Department of Pharmacology and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA, 90033, USA.
  • Chen JF; Center for Craniofacial Molecular Biology, University of Southern California (USC), Los Angeles, CA, 90033, USA. Jianfu@usc.edu.
Nat Commun ; 10(1): 2612, 2019 06 13.
Article em En | MEDLINE | ID: mdl-31197141
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Proteínas Repressoras / Cinesinas / Proteínas de Ciclo Celular / Microcefalia / Proteínas Associadas aos Microtúbulos / Proteínas do Tecido Nervoso Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Proteínas Repressoras / Cinesinas / Proteínas de Ciclo Celular / Microcefalia / Proteínas Associadas aos Microtúbulos / Proteínas do Tecido Nervoso Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido