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Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies.
Park, Tae-Eun; Mustafaoglu, Nur; Herland, Anna; Hasselkus, Ryan; Mannix, Robert; FitzGerald, Edward A; Prantil-Baun, Rachelle; Watters, Alexander; Henry, Olivier; Benz, Maximilian; Sanchez, Henry; McCrea, Heather J; Goumnerova, Liliana Christova; Song, Hannah W; Palecek, Sean P; Shusta, Eric; Ingber, Donald E.
Afiliação
  • Park TE; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, 02115, USA.
  • Mustafaoglu N; Ulsan National Institute of Science and Technology (UNIST), UNIST-gil 50, Ulsan, 44919, Republic of Korea.
  • Herland A; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, 02115, USA.
  • Hasselkus R; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, 02115, USA.
  • Mannix R; Division of Micro and Nanosystems, KTH Royal Institute of Technology, Stockholm, Sweden.
  • FitzGerald EA; Swedish Medical Nanoscience Center, Department of Neuroscience, Karolinska Institute, Stockholm, Sweden.
  • Prantil-Baun R; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, 02115, USA.
  • Watters A; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, 02115, USA.
  • Henry O; Vascular Biology Program and Department of Surgery, Boston Children's Hospital and Harvard Medical School, Boston, MA, 02115, USA.
  • Benz M; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, 02115, USA.
  • Sanchez H; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, 02115, USA.
  • McCrea HJ; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, 02115, USA.
  • Goumnerova LC; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, 02115, USA.
  • Song HW; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, 02115, USA.
  • Palecek SP; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, 02115, USA.
  • Shusta E; Department of Neurosurgery, Boston Children's Hospital and Harvard Medical School, Boston, MA, 02115, USA.
  • Ingber DE; Department of Neurosurgery, Boston Children's Hospital and Harvard Medical School, Boston, MA, 02115, USA.
Nat Commun ; 10(1): 2621, 2019 06 13.
Article em En | MEDLINE | ID: mdl-31197168
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Barreira Hematoencefálica / Sistemas de Liberação de Medicamentos / Células Endoteliais / Microfluídica Tipo de estudo: Guideline Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Barreira Hematoencefálica / Sistemas de Liberação de Medicamentos / Células Endoteliais / Microfluídica Tipo de estudo: Guideline Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido