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Design, synthesis and biological evaluation of novel 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole triazole derivatives as potent TRPV1 antagonists.
Li, Jinyu; Nie, Cunbin; Qiao, Yue; Hu, Jing; Li, Qifei; Wang, Qiang; Pu, Xiaohui; Yan, Lin; Qian, Hai.
Afiliação
  • Li J; Institute for Innovative Drug Design and Evaluation, School of Pharmacy, Henan University, N. Jinming Ave., Kaifeng, Henan, 475004, China.
  • Nie C; Institute for Innovative Drug Design and Evaluation, School of Pharmacy, Henan University, N. Jinming Ave., Kaifeng, Henan, 475004, China.
  • Qiao Y; Institute for Innovative Drug Design and Evaluation, School of Pharmacy, Henan University, N. Jinming Ave., Kaifeng, Henan, 475004, China.
  • Hu J; Institute for Innovative Drug Design and Evaluation, School of Pharmacy, Henan University, N. Jinming Ave., Kaifeng, Henan, 475004, China.
  • Li Q; State Key Laboratory of Natural Medicines, Center of Drug Discovery, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, Jiangsu, 210009, China.
  • Wang Q; School of Pharmaceutical Sciences, South-Central University for Nationalities, 182 Minyuan Road, Wuhan, Hubei, 430074, China.
  • Pu X; Institute for Innovative Drug Design and Evaluation, School of Pharmacy, Henan University, N. Jinming Ave., Kaifeng, Henan, 475004, China.
  • Yan L; Institute for Innovative Drug Design and Evaluation, School of Pharmacy, Henan University, N. Jinming Ave., Kaifeng, Henan, 475004, China. Electronic address: yanlin0378@163.com.
  • Qian H; State Key Laboratory of Natural Medicines, Center of Drug Discovery, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, Jiangsu, 210009, China. Electronic address: qianhai24@163.com.
Eur J Med Chem ; 178: 433-445, 2019 Sep 15.
Article em En | MEDLINE | ID: mdl-31202991
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triazóis / Desenho de Fármacos / Canais de Cátion TRPV / Indóis Limite: Animals Idioma: En Revista: Eur J Med Chem Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: França
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triazóis / Desenho de Fármacos / Canais de Cátion TRPV / Indóis Limite: Animals Idioma: En Revista: Eur J Med Chem Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: França