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Outflanking immunodominance to target subdominant broadly neutralizing epitopes.
Angeletti, Davide; Kosik, Ivan; Santos, Jefferson J S; Yewdell, William T; Boudreau, Carolyn M; Mallajosyula, Vamsee V A; Mankowski, Madeleine C; Chambers, Michael; Prabhakaran, Madhu; Hickman, Heather D; McDermott, Adrian B; Alter, Galit; Chaudhuri, Jayanta; Yewdell, Jonathan W.
Afiliação
  • Angeletti D; Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892; davide.angeletti@gu.se jyewdell@niaid.nih.gov.
  • Kosik I; Department of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg, 40530 Gothenburg, Sweden.
  • Santos JJS; Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
  • Yewdell WT; Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
  • Boudreau CM; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065.
  • Mallajosyula VVA; Ragon Institute of MGH, MIT, and Harvard University, Cambridge, MA 02139.
  • Mankowski MC; PhD Program in Virology, Division of Medical Sciences, Harvard University, Boston, MA 02115.
  • Chambers M; Institute for Immunity, Transplantation and Infection, Stanford University, Stanford, CA 94305.
  • Prabhakaran M; Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
  • Hickman HD; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
  • McDermott AB; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
  • Alter G; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
  • Chaudhuri J; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
  • Yewdell JW; Ragon Institute of MGH, MIT, and Harvard University, Cambridge, MA 02139.
Proc Natl Acad Sci U S A ; 116(27): 13474-13479, 2019 07 02.
Article em En | MEDLINE | ID: mdl-31213541

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus da Influenza A / Vacinas contra Influenza / Epitopos Imunodominantes / Anticorpos Neutralizantes / Hemaglutininas / Epitopos Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2019 Tipo de documento: Article País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus da Influenza A / Vacinas contra Influenza / Epitopos Imunodominantes / Anticorpos Neutralizantes / Hemaglutininas / Epitopos Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2019 Tipo de documento: Article País de publicação: Estados Unidos