Dissecting the Pharmacodynamics and Pharmacokinetics of MSCs to Overcome Limitations in Their Clinical Translation.

Salvadori, Michela; Cesari, Nicola; Murgia, Alba; Puccini, Paola; Riccardi, Benedetta; Dominici, Massimo

Salvadori, Michela; Cesari, Nicola; Murgia, Alba; Puccini, Paola; Riccardi, Benedetta; Dominici, Massimo.

Afiliação

Salvadori M; Department of Pharmacokinetics, Biochemistry and Metabolism, Chiesi Farmaceutici S.p.A, 43122 Parma, Italy.
Cesari N; Department of Pharmacokinetics, Biochemistry and Metabolism, Chiesi Farmaceutici S.p.A, 43122 Parma, Italy.
Murgia A; Laboratory of Cellular Therapy, Division of Oncology, Department of Medical and Surgical Sciences for Children and Adults, University Hospital of Modena and Reggio Emilia, Modena, Italy.
Puccini P; Department of Pharmacokinetics, Biochemistry and Metabolism, Chiesi Farmaceutici S.p.A, 43122 Parma, Italy.
Riccardi B; Department of Pharmacokinetics, Biochemistry and Metabolism, Chiesi Farmaceutici S.p.A, 43122 Parma, Italy.
Dominici M; Laboratory of Cellular Therapy, Division of Oncology, Department of Medical and Surgical Sciences for Children and Adults, University Hospital of Modena and Reggio Emilia, Modena, Italy.

Mol Ther Methods Clin Dev ; 14: 1-15, 2019 Sep 13.

Article em En | MEDLINE | ID: mdl-31236426

Palavras-chave

MSCs; PK-PD model; biodistribution; clinical translation; lung regeneration; mesenchymal cells; mesenchymal stromal cells; pharmacodynamics; pharmacokinetics; stem cell therapy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Mol Ther Methods Clin Dev Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Itália País de publicação: Estados Unidos

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