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Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa.
Watson, Hunna J; Yilmaz, Zeynep; Thornton, Laura M; Hübel, Christopher; Coleman, Jonathan R I; Gaspar, Héléna A; Bryois, Julien; Hinney, Anke; Leppä, Virpi M; Mattheisen, Manuel; Medland, Sarah E; Ripke, Stephan; Yao, Shuyang; Giusti-Rodríguez, Paola; Hanscombe, Ken B; Purves, Kirstin L; Adan, Roger A H; Alfredsson, Lars; Ando, Tetsuya; Andreassen, Ole A; Baker, Jessica H; Berrettini, Wade H; Boehm, Ilka; Boni, Claudette; Perica, Vesna Boraska; Buehren, Katharina; Burghardt, Roland; Cassina, Matteo; Cichon, Sven; Clementi, Maurizio; Cone, Roger D; Courtet, Philippe; Crow, Scott; Crowley, James J; Danner, Unna N; Davis, Oliver S P; de Zwaan, Martina; Dedoussis, George; Degortes, Daniela; DeSocio, Janiece E; Dick, Danielle M; Dikeos, Dimitris; Dina, Christian; Dmitrzak-Weglarz, Monika; Docampo, Elisa; Duncan, Laramie E; Egberts, Karin; Ehrlich, Stefan; Escaramís, Geòrgia; Esko, Tõnu.
Afiliação
  • Watson HJ; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Yilmaz Z; School of Psychology, Curtin University, Perth, Western Australia, Australia.
  • Thornton LM; School of Paediatrics and Child Health, University of Western Australia, Perth, Western Australia, Australia.
  • Hübel C; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Coleman JRI; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Gaspar HA; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Bryois J; Institute of Psychiatry, Psychology and Neuroscience, Social, Genetic and Developmental Psychiatry (SGDP) Centre, King's College London, London, UK.
  • Hinney A; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
  • Leppä VM; Institute of Psychiatry, Psychology and Neuroscience, Social, Genetic and Developmental Psychiatry (SGDP) Centre, King's College London, London, UK.
  • Mattheisen M; National Institute for Health Research Biomedical Research Centre, King's College London and South London and Maudsley National Health Service Foundation Trust, London, UK.
  • Medland SE; Institute of Psychiatry, Psychology and Neuroscience, Social, Genetic and Developmental Psychiatry (SGDP) Centre, King's College London, London, UK.
  • Ripke S; National Institute for Health Research Biomedical Research Centre, King's College London and South London and Maudsley National Health Service Foundation Trust, London, UK.
  • Yao S; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
  • Giusti-Rodríguez P; Department of Child and Adolescent Psychiatry, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
  • Hanscombe KB; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Purves KL; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Adan RAH; Department of Psychiatry, Psychosomatics and Psychotherapy, University of Würzburg, Würzburg, Germany.
  • Alfredsson L; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Ando T; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.
  • Andreassen OA; Stanley Center for Psychiatric Research, Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.
  • Baker JH; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany.
  • Berrettini WH; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
  • Boehm I; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Perica VB; Department of Medical and Molecular Genetics, King's College London, Guy's Hospital, London, UK.
  • Buehren K; Institute of Psychiatry, Psychology and Neuroscience, Social, Genetic and Developmental Psychiatry (SGDP) Centre, King's College London, London, UK.
  • Cassina M; Brain Center Rudolf Magnus, Department of Translational Neuroscience, University Medical Center Utrecht, Utrecht, the Netherlands.
  • Cichon S; Center for Eating Disorders Rintveld, Altrecht Mental Health Institute, Zeist, the Netherlands.
  • Clementi M; Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
  • Cone RD; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Courtet P; Department of Behavioral Medicine, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan.
  • Crow S; NORMENT KG Jebsen Centre, Division of Mental Health and Addiction, University of Oslo, Oslo University Hospital, Oslo, Norway.
  • Crowley JJ; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Danner UN; Department of Psychiatry, Center for Neurobiology and Behavior, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
  • Davis OSP; Division of Psychological and Social Medicine and Developmental Neurosciences, Faculty of Medicine, Technische Universität Dresden, Dresden, Germany.
  • de Zwaan M; INSERM 1266, Institute of Psychiatry and Neuroscience of Paris, Paris, France.
  • Dedoussis G; Wellcome Sanger Institute, Hinxton, UK.
  • Degortes D; Department of Medical Biology, School of Medicine, University of Split, Split, Croatia.
  • DeSocio JE; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, RWTH Aachen University, Aachen, Germany.
  • Dick DM; Department of Child and Adolescent Psychiatry, Klinikum Frankfurt/Oder, Frankfurt, Germany.
  • Dikeos D; Clinical Genetics Unit, Department of Woman and Child Health, University of Padova, Padova, Italy.
  • Dina C; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland.
  • Dmitrzak-Weglarz M; Clinical Genetics Unit, Department of Woman and Child Health, University of Padova, Padova, Italy.
  • Docampo E; Life Sciences Institute and Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.
  • Duncan LE; Department of Emergency Psychiatry and Post-Acute Care, CHRU Montpellier, University of Montpellier, Montpellier, France.
  • Egberts K; Department of Psychiatry, University of Minnesota, Minneapolis, MN, USA.
  • Ehrlich S; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Escaramís G; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Esko T; Center for Eating Disorders Rintveld, Altrecht Mental Health Institute, Zeist, the Netherlands.
Nat Genet ; 51(8): 1207-1214, 2019 08.
Article em En | MEDLINE | ID: mdl-31308545
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anorexia Nervosa / Predisposição Genética para Doença / Genômica / Locos de Características Quantitativas / Estudo de Associação Genômica Ampla / Transtornos Mentais / Doenças Metabólicas Tipo de estudo: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male Idioma: En Revista: Nat Genet Assunto da revista: GENETICA MEDICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anorexia Nervosa / Predisposição Genética para Doença / Genômica / Locos de Características Quantitativas / Estudo de Associação Genômica Ampla / Transtornos Mentais / Doenças Metabólicas Tipo de estudo: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male Idioma: En Revista: Nat Genet Assunto da revista: GENETICA MEDICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos