O-Mannosylation Affords a Glycopeptide Hydrogel with Inherent Antibacterial Activities against E. coli via Multivalent Interactions between Lectins and Supramolecular Assemblies.

Li, Jing; Liang, Shufeng; Yan, Yufei; Tian, Xin; Li, Xinming

Li, Jing; Liang, Shufeng; Yan, Yufei; Tian, Xin; Li, Xinming.

Afiliação

Li J; Department of Polymer Science and Engineering, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, 215123, China.
Liang S; State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou, 215123, China.
Yan Y; Department of Molecular Biology, Shanxi Cancer Hospital and Institute, Affiliated Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030013, China.
Tian X; Shanghai Key Laboratory for Bone and Joint Diseases, Shanghai Institute of Orthopaedics and Traumatology, Shanghai Ruijin Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, 200025, China.
Li X; State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou, 215123, China.

Macromol Biosci ; 19(9): e1900124, 2019 09.

Article em En | MEDLINE | ID: mdl-31310440

Assuntos

Anti-Infecciosos/farmacologia; Escherichia coli/efeitos dos fármacos; Glicopeptídeos/farmacologia; Hidrogéis/farmacologia; Lectinas/metabolismo; Manose/química; Animais; Materiais Biocompatíveis/farmacologia; Escherichia coli/ultraestrutura; Camundongos; Testes de Sensibilidade Microbiana; Células NIH 3T3; Pele/efeitos dos fármacos; Pele/patologia; Espectroscopia de Infravermelho com Transformada de Fourier; Cicatrização/efeitos dos fármacos

Palavras-chave

glycopeptide; hydrogel; mannose; self-assembly; wound dressing

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glicopeptídeos / Hidrogéis / Escherichia coli / Lectinas / Manose / Anti-Infecciosos Limite: Animals Idioma: En Revista: Macromol Biosci Assunto da revista: BIOQUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Alemanha

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