Strengths and limitations of morphological and behavioral analyses in detecting dopaminergic deficiency in Caenorhabditis elegans.

Smith, Latasha L; Ryde, Ian T; Hartman, Jessica H; Romersi, Riccardo F; Markovich, Zachary; Meyer, Joel N

Smith, Latasha L; Ryde, Ian T; Hartman, Jessica H; Romersi, Riccardo F; Markovich, Zachary; Meyer, Joel N.

Afiliação

Smith LL; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, United States; Integrated Toxicology and Environmental Health Program, Duke University, Durham, NC, United States. Electronic address: latasha.l.smith@duke.edu.
Ryde IT; Integrated Toxicology and Environmental Health Program, Duke University, Durham, NC, United States; Nicholas School of the Environment, Duke University, Durham, NC, United States. Electronic address: ian.ryde@duke.edu.
Hartman JH; Nicholas School of the Environment, Duke University, Durham, NC, United States. Electronic address: jessica.h.hartman@duke.edu.
Romersi RF; Nicholas School of the Environment, Duke University, Durham, NC, United States. Electronic address: riccardo.romersi@duke.edu.
Markovich Z; Nicholas School of the Environment, Duke University, Durham, NC, United States. Electronic address: zachary.markovich@duke.edu.
Meyer JN; Integrated Toxicology and Environmental Health Program, Duke University, Durham, NC, United States; Nicholas School of the Environment, Duke University, Durham, NC, United States. Electronic address: joel.meyer@duke.edu.

Neurotoxicology ; 74: 209-220, 2019 09.

Article em En | MEDLINE | ID: mdl-31323240

Assuntos

Comportamento Animal/efeitos dos fármacos; Caenorhabditis elegans; Dopamina/deficiência; Neurônios Dopaminérgicos/efeitos dos fármacos; Neurônios Dopaminérgicos/patologia; Doenças Neurodegenerativas/patologia; Animais; Animais Geneticamente Modificados; Aprendizagem da Esquiva/efeitos dos fármacos; Proteínas de Caenorhabditis elegans; Transportador 2 de Aminoácidos Catiônicos/genética; Dopamina/metabolismo; Comportamento Exploratório/efeitos dos fármacos; Regulação da Expressão Gênica; Hidroxidopaminas/toxicidade; Larva; Locomoção/efeitos dos fármacos

Palavras-chave

Behavior; C. elegans; Dopamine; Locomotion; Neurodegeneration; cat-2

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Comportamento Animal / Dopamina / Caenorhabditis elegans / Doenças Neurodegenerativas / Neurônios Dopaminérgicos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Neurotoxicology Ano de publicação: 2019 Tipo de documento: Article País de publicação: Holanda

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google