Detection of 13 Ginsenosides (Rb1, Rb2, Rc, Rd, Re, Rf, Rg1, Rg3, Rh2, F1, Compound K, 20(<i>S</i>)-Protopanaxadiol, and 20(<i>S</i>)-Protopanaxatriol) in Human Plasma and Application of the Analytical Method to Human Pharmacokinetic Studies Following Two Week-Repeated Administration of Red Ginseng Extract.

Jin, Sojeong; Jeon, Ji-Hyeon; Lee, Sowon; Kang, Woo Youl; Seong, Sook Jin; Yoon, Young-Ran; Choi, Min-Koo; Song, Im-Sook

Detection of 13 Ginsenosides (Rb1, Rb2, Rc, Rd, Re, Rf, Rg1, Rg3, Rh2, F1, Compound K, 20(S)-Protopanaxadiol, and 20(S)-Protopanaxatriol) in Human Plasma and Application of the Analytical Method to Human Pharmacokinetic Studies Following Two Week-Repeated Administration of Red Ginseng Extract.

Jin, Sojeong; Jeon, Ji-Hyeon; Lee, Sowon; Kang, Woo Youl; Seong, Sook Jin; Yoon, Young-Ran; Choi, Min-Koo; Song, Im-Sook.

Afiliação

Jin S; College of Pharmacy, Dankook University, Cheon-an 31116, Korea.
Jeon JH; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu 41566, Korea.
Lee S; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu 41566, Korea.
Kang WY; Clinical Trial Center, Kyungpook National University Hospital, Daegu 41944, Korea.
Seong SJ; Department of Biomedical Science, BK21 Plus KNU Bio-Medical Convergence Program for Creative Talent, College of Medicine, Kyungpook National University, Daegu 41944, Korea.
Yoon YR; Clinical Trial Center, Kyungpook National University Hospital, Daegu 41944, Korea.
Choi MK; Department of Biomedical Science, BK21 Plus KNU Bio-Medical Convergence Program for Creative Talent, College of Medicine, Kyungpook National University, Daegu 41944, Korea.
Song IS; Clinical Trial Center, Kyungpook National University Hospital, Daegu 41944, Korea.

Molecules ; 24(14)2019 Jul 18.

Article em En | MEDLINE | ID: mdl-31323835

Assuntos

Ginsenosídeos/sangue; Ginsenosídeos/química; Panax/química; Extratos Vegetais/sangue; Extratos Vegetais/química; Ginsenosídeos/farmacocinética; Humanos; Redes e Vias Metabólicas; Estrutura Molecular; Extratos Vegetais/farmacocinética; Reprodutibilidade dos Testes; Sensibilidade e Especificidade; Espectrometria de Massas em Tandem

Palavras-chave

ginsenosides; human; pharmacokinetics; red ginseng extract

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Ginsenosídeos / Panax Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de publicação: Suíça

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