Evolution from Covalent to Self-Assembled PAMAM-Based Dendrimers as Nanovectors for siRNA Delivery in Cancer by Coupled In Silico-Experimental Studies. Part I: Covalent siRNA Nanocarriers.

Marson, Domenico; Laurini, Erik; Aulic, Suzana; Fermeglia, Maurizio; Pricl, Sabrina

Marson, Domenico; Laurini, Erik; Aulic, Suzana; Fermeglia, Maurizio; Pricl, Sabrina.

Afiliação

Marson D; Molecular Biology and Nanotechnology Laboratory (MolBNL@UniTS), Department of Engineering and Architecture, University of Trieste, 34127 Trieste, Italy.
Laurini E; Molecular Biology and Nanotechnology Laboratory (MolBNL@UniTS), Department of Engineering and Architecture, University of Trieste, 34127 Trieste, Italy. erik.laurini@dia.units.it.
Aulic S; Molecular Biology and Nanotechnology Laboratory (MolBNL@UniTS), Department of Engineering and Architecture, University of Trieste, 34127 Trieste, Italy.
Fermeglia M; Molecular Biology and Nanotechnology Laboratory (MolBNL@UniTS), Department of Engineering and Architecture, University of Trieste, 34127 Trieste, Italy.
Pricl S; Molecular Biology and Nanotechnology Laboratory (MolBNL@UniTS), Department of Engineering and Architecture, University of Trieste, 34127 Trieste, Italy.

Pharmaceutics ; 11(7)2019 Jul 18.

Article em En | MEDLINE | ID: mdl-31323863

Palavras-chave

PAMAM dendrimers; RNAi therapeutics; covalent dendrimers; gene silencing; nanovectors; siRNA delivery

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Pharmaceutics Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Itália País de publicação: Suíça

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