Prodigiosin Promotes Nrf2 Activation to Inhibit Oxidative Stress Induced by Microcystin-LR in HepG2 Cells.

Chen, Jihua; Li, Yuji; Liu, Fuqiang; Hou, De-Xing; Xu, Jingjing; Zhao, Xinying; Yang, Fei; Feng, Xiangling

Chen, Jihua; Li, Yuji; Liu, Fuqiang; Hou, De-Xing; Xu, Jingjing; Zhao, Xinying; Yang, Fei; Feng, Xiangling.

Afiliação

Chen J; Xiangya School of Public Health, Central South University, Changsha 410128, Hunan, China.
Li Y; Xiangya School of Public Health, Central South University, Changsha 410128, Hunan, China.
Liu F; Department of Public Health Emergency Treatment, Hunan Center for Disease Control and Prevention (CDC), Changsha 410005, Hunan, China.
Hou DX; Department of Food Science and Biotechnology, Faculty of Agriculture, Kagoshima University, Kagoshima 890-0065, Japan.
Xu J; Xiangya School of Public Health, Central South University, Changsha 410128, Hunan, China.
Zhao X; Xiangya School of Public Health, Central South University, Changsha 410128, Hunan, China.
Yang F; Xiangya School of Public Health, Central South University, Changsha 410128, Hunan, China. phfyang@csu.edu.cn.
Feng X; Xiangya School of Public Health, Central South University, Changsha 410128, Hunan, China. fengxl2011@csu.edu.cn.

Toxins (Basel) ; 11(7)2019 07 12.

Article em En | MEDLINE | ID: mdl-31336817

Assuntos

Microcistinas/toxicidade; Fator 2 Relacionado a NF-E2/metabolismo; Prodigiosina/farmacologia; Células Hep G2; Humanos; Toxinas Marinhas; Fator 2 Relacionado a NF-E2/genética; Estresse Oxidativo/efeitos dos fármacos; RNA Interferente Pequeno/genética; Espécies Reativas de Oxigênio/metabolismo

Palavras-chave

Nrf2; ROS; microcystin-LR; prodigiosin; ubiquitination

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Prodigiosina / Fator 2 Relacionado a NF-E2 / Microcistinas Limite: Humans Idioma: En Revista: Toxins (Basel) Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Suíça

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