MicroRNA-25-5p counteracts oxidized LDL-induced pathological changes by targeting neuronal growth regulator 1 (NEGR1) in human brain micro-vessel endothelial cells.

Zhang, Qi; Liu, Chun; Li, Qiang; Li, Jianan; Wu, Yina; Liu, Jianmin

Zhang, Qi; Liu, Chun; Li, Qiang; Li, Jianan; Wu, Yina; Liu, Jianmin.

Afiliação

Zhang Q; Department of Cerebrovascular Diseases, Blue Cross Brain Hospital Affiliated to Tongji University, Shanghai, 201101, China. Electronic address: zhqiciao@126.com.
Liu C; Department of Cerebrovascular Diseases, Blue Cross Brain Hospital Affiliated to Tongji University, Shanghai, 201101, China.
Li Q; Department of Neurosurgery, Changhai Hospital of Shanghai Affiliated to Naval Military Medical University, Shanghai, 200433, China.
Li J; Department of Neurosurgery, Changhai Hospital of Shanghai Affiliated to Naval Military Medical University, Shanghai, 200433, China.
Wu Y; Department of Neurosurgery, Changhai Hospital of Shanghai Affiliated to Naval Military Medical University, Shanghai, 200433, China.
Liu J; Department of Neurosurgery, Changhai Hospital of Shanghai Affiliated to Naval Military Medical University, Shanghai, 200433, China. Electronic address: liu118.vip@163.com.

Biochimie ; 165: 141-149, 2019 Oct.

Article em En | MEDLINE | ID: mdl-31365884

Assuntos

Encéfalo/irrigação sanguínea; Moléculas de Adesão Celular Neuronais/metabolismo; Endotélio Vascular/metabolismo; Endotélio Vascular/patologia; Lipoproteínas LDL/metabolismo; MicroRNAs/fisiologia; Apoptose; Linhagem Celular; Movimento Celular; Proliferação de Células; Proteínas Ligadas por GPI/metabolismo; Humanos; Janus Quinase 2/metabolismo; Microvasos/patologia; Espécies Reativas de Oxigênio/metabolismo; Fator de Transcrição STAT3/metabolismo; Transdução de Sinais

Palavras-chave

Human brain microvessel endothelial cells; JAK/STAT signaling pathway; MicroRNA-255p; Neuronal growth regulator 1; Oxidized low-density lipoprotein

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Endotélio Vascular / Moléculas de Adesão Celular Neuronais / MicroRNAs / Lipoproteínas LDL Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Biochimie Ano de publicação: 2019 Tipo de documento: Article País de publicação: França

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