Obsessive compulsive disorder (OCD): Current treatments and a framework for neurotherapeutic research.
Adv Pharmacol
; 86: 237-271, 2019.
Article
em En
| MEDLINE
| ID: mdl-31378254
ABSTRACT
We briefly review current approaches to the diagnosis and treatment of OCD, noting their lack of a strong theoretical foundation. In keeping with the Research Domain Criteria project (RDoC) calls for reconceptualizing psychopathology in ways that better link up with normal brain systems, we advance an adaptationist, brain-network perspective on OCD and propose that OCD represents a dysfunction in the stopping dynamics of a normal brain network that evolved to handle potential danger. We then illustrate how this theoretical perspective can be used to organize possibilities for research on neurotherapeutics for OCD and suggest novel directions for future work.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transtorno Obsessivo-Compulsivo
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
Adv Pharmacol
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Canadá