Responses in the crucian carp (Carassius auratus) exposed to environmentally relevant concentration of 17&#945;-Ethinylestradiol based on metabolomics.

Zhou, Xinyi; Li, Yue; Li, Haipu; Yang, Zhaoguang; Zuo, Chenchen

Responses in the crucian carp (Carassius auratus) exposed to environmentally relevant concentration of 17α-Ethinylestradiol based on metabolomics.

Zhou, Xinyi; Li, Yue; Li, Haipu; Yang, Zhaoguang; Zuo, Chenchen.

Afiliação

Zhou X; Center for Environment and Water Resources, College of Chemistry and Chemical Engineering, Central South University, Changsha, China; Key Laboratory of Hunan Province for Water Environment and Agriculture Product Safety, Changsha, China. Electronic address: zhouxinyi@csu.edu.cn.
Li Y; Center for Environment and Water Resources, College of Chemistry and Chemical Engineering, Central South University, Changsha, China; Key Laboratory of Hunan Province for Water Environment and Agriculture Product Safety, Changsha, China. Electronic address: yuelli@csu.edu.cn.
Li H; Center for Environment and Water Resources, College of Chemistry and Chemical Engineering, Central South University, Changsha, China; Key Laboratory of Hunan Province for Water Environment and Agriculture Product Safety, Changsha, China. Electronic address: lihaipu@csu.edu.cn.
Yang Z; Center for Environment and Water Resources, College of Chemistry and Chemical Engineering, Central South University, Changsha, China; Key Laboratory of Hunan Province for Water Environment and Agriculture Product Safety, Changsha, China. Electronic address: zgyang@csu.edu.cn.
Zuo C; Center for Environment and Water Resources, College of Chemistry and Chemical Engineering, Central South University, Changsha, China; Key Laboratory of Hunan Province for Water Environment and Agriculture Product Safety, Changsha, China. Electronic address: 15303179643@163.com.

Ecotoxicol Environ Saf ; 183: 109501, 2019 Nov 15.

Article em En | MEDLINE | ID: mdl-31401330

Assuntos

Disruptores Endócrinos/toxicidade; Etinilestradiol/toxicidade; Carpa Dourada/metabolismo; Metaboloma/efeitos dos fármacos; Poluentes Químicos da Água/toxicidade; Animais; Exposição Ambiental/efeitos adversos; Metabolômica; Reprodução/efeitos dos fármacos; Esteroides/metabolismo

Palavras-chave

17α-Ethinylestradiol; 17α-ethynylestradiol (EE2); 17ß-estradiol (E2); Adenosine triphosphate (ATP); Bioaccumulation; Endocrine disrupting chemical (EDC); Estrone (E1); Gas chromatography-mass spectrometry (GC-MS); Gonad; Gonadosomatic index (GSI); Hepatosomatic index (HSI); Kidney; MS-Assisted resolution of signals (MARS); Metabolomics; Nicotinamide adenine dinucleotide phosphate (NADPH); One-way analysis of variance (ANOVA); Partial least-squares discriminant analysis (PLS-DA); Principal component analysis (PCA); Quality control (QC); Reactive oxygen species (ROS); The area under the receiver operating characteristic curve (AUC); The citrate cycle (TCA cycle); The total ion chromatograms (TICs); Variable importance on projection (VIP)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Poluentes Químicos da Água / Carpa Dourada / Etinilestradiol / Disruptores Endócrinos / Metaboloma Limite: Animals Idioma: En Revista: Ecotoxicol Environ Saf Ano de publicação: 2019 Tipo de documento: Article País de publicação: Holanda

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