Metabolic engineering of Bacillus megaterium for heparosan biosynthesis using Pasteurella multocida heparosan synthase, PmHS2.

Williams, Asher; Gedeon, Kamil S; Vaidyanathan, Deepika; Yu, Yanlei; Collins, Cynthia H; Dordick, Jonathan S; Linhardt, Robert J; Koffas, Mattheos A G

Williams, Asher; Gedeon, Kamil S; Vaidyanathan, Deepika; Yu, Yanlei; Collins, Cynthia H; Dordick, Jonathan S; Linhardt, Robert J; Koffas, Mattheos A G.

Afiliação

Williams A; Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.
Gedeon KS; Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.
Vaidyanathan D; Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.
Yu Y; Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, USA.
Collins CH; Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.
Dordick JS; Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.
Linhardt RJ; Department of Biology, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.
Koffas MAG; Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.

Microb Cell Fact ; 18(1): 132, 2019 Aug 12.

Article em En | MEDLINE | ID: mdl-31405374

Assuntos

Bacillus megaterium/genética; Bacillus megaterium/metabolismo; Dissacarídeos/biossíntese; Glicosiltransferases/metabolismo; Proteínas de Bactérias/genética; Proteínas de Bactérias/metabolismo; Vias Biossintéticas; RNA Polimerases Dirigidas por DNA/genética; Engenharia Genética; Glicosiltransferases/genética; Engenharia Metabólica; Pasteurella multocida/enzimologia; Proteínas Virais/genética

Palavras-chave

Bacillus megaterium; Glycosaminoglycans; Heparosan; Heparosan synthase; Metabolic engineering

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bacillus megaterium / Glicosiltransferases / Dissacarídeos Idioma: En Revista: Microb Cell Fact Assunto da revista: BIOTECNOLOGIA / MICROBIOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido

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