Viburnum pichinchense methanol extract exerts anti-inflammatory effects via targeting the NF-&#954;B and caspase-11 non-canonical inflammasome pathways in macrophages.

Hwang, So-Hyeon; Lorz, Laura Rojas; Yi, Dong-Keun; Noh, Jin Kyoung; Yi, Young-Su; Cho, Jae Youl

Viburnum pichinchense methanol extract exerts anti-inflammatory effects via targeting the NF-κB and caspase-11 non-canonical inflammasome pathways in macrophages.

Hwang, So-Hyeon; Lorz, Laura Rojas; Yi, Dong-Keun; Noh, Jin Kyoung; Yi, Young-Su; Cho, Jae Youl.

Afiliação

Hwang SH; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon, 16419, South Korea. Electronic address: sohyun031195@naver.com.
Lorz LR; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon, 16419, South Korea. Electronic address: laurisrl@gmail.com.
Yi DK; International Biological Material Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 34141, South Korea. Electronic address: lydian78@kribb.re.kr.
Noh JK; Instituto de BioEconomia, El Batan, Quito, 170135, Ecuador. Electronic address: njk1201@hotmail.com.
Yi YS; Department of Pharmaceutical and Biomedical Engineering, Cheongju University, Cheongju, 28503, South Korea. Electronic address: ysyi@cju.ac.kr.
Cho JY; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon, 16419, South Korea. Electronic address: jaecho@skku.edu.

J Ethnopharmacol ; 245: 112161, 2019 Dec 05.

Article em En | MEDLINE | ID: mdl-31419499

Assuntos

Anti-Inflamatórios/farmacologia; Caspases Iniciadoras/metabolismo; Inflamassomos/metabolismo; NF-kappa B/genética; Extratos Vegetais/farmacologia; Viburnum; Animais; Anti-Inflamatórios/uso terapêutico; Ciclo-Oxigenase 2/genética; Citocinas/genética; Etanol; Gastrite/induzido quimicamente; Gastrite/tratamento farmacológico; Células HEK293; Humanos; Ácido Clorídrico; Lipopolissacarídeos; Macrófagos Peritoneais/efeitos dos fármacos; Macrófagos Peritoneais/metabolismo; Metanol/química; Camundongos; Óxido Nítrico Sintase Tipo II/genética; Extratos Vegetais/uso terapêutico; Células RAW 264.7; Solventes/química

Palavras-chave

Anti-inflammatory; Caspase-11 non-canonical inflammasome; Gastritis; Macrophage; NF-κB; Viburnum pichinchense

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Extratos Vegetais / NF-kappa B / Viburnum / Caspases Iniciadoras / Inflamassomos / Anti-Inflamatórios Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Ethnopharmacol Ano de publicação: 2019 Tipo de documento: Article

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