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Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy.
Wu, Tiffany; Dejanovic, Borislav; Gandham, Vineela D; Gogineni, Alvin; Edmonds, Rose; Schauer, Stephen; Srinivasan, Karpagam; Huntley, Melanie A; Wang, Yuanyuan; Wang, Tzu-Ming; Hedehus, Maj; Barck, Kai H; Stark, Maya; Ngu, Hai; Foreman, Oded; Meilandt, William J; Elstrott, Justin; Chang, Michael C; Hansen, David V; Carano, Richard A D; Sheng, Morgan; Hanson, Jesse E.
Afiliação
  • Wu T; Department of Neuroscience, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Dejanovic B; Department of Neuroscience, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Gandham VD; Department of Biomedical Imaging, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Gogineni A; Department of Biomedical Imaging, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Edmonds R; Department of Biomarker Development, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Schauer S; Department of Biomarker Development, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Srinivasan K; Department of Neuroscience, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Huntley MA; Department of Neuroscience, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA; Department of Bioinformatics, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Wang Y; Department of Neuroscience, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Wang TM; Department of Neuroscience, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Hedehus M; Department of Biomedical Imaging, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Barck KH; Department of Biomedical Imaging, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Stark M; Department of Pathology, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Ngu H; Department of Pathology, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Foreman O; Department of Pathology, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Meilandt WJ; Department of Neuroscience, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Elstrott J; Department of Biomedical Imaging, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Chang MC; Department of Biomarker Development, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Hansen DV; Department of Neuroscience, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Carano RAD; Department of Biomedical Imaging, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Sheng M; Department of Neuroscience, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Hanson JE; Department of Neuroscience, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA. Electronic address: hanson.jesse@gene.com.
Cell Rep ; 28(8): 2111-2123.e6, 2019 08 20.
Article em En | MEDLINE | ID: mdl-31433986
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complemento C3 / Tauopatias / Doença de Alzheimer / Amiloidose / Degeneração Neural Limite: Animals / Female / Humans / Male Idioma: En Revista: Cell Rep Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complemento C3 / Tauopatias / Doença de Alzheimer / Amiloidose / Degeneração Neural Limite: Animals / Female / Humans / Male Idioma: En Revista: Cell Rep Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos