Interleukin 6 Promotes <i>Brucella abortus</i> Clearance by Controlling Bactericidal Activity of Macrophages and CD8<sup>+</sup> T Cell Differentiation.

Hop, Huynh Tan; Huy, Tran Xuan Ngoc; Reyes, Alisha Wehdnesday Bernardo; Arayan, Lauren Togonon; Vu, Son Hai; Min, WonGi; Lee, Hu Jang; Kang, Chang Keun; Kim, Dong Hee; Tark, Dong Seob; Kim, Suk

Interleukin 6 Promotes Brucella abortus Clearance by Controlling Bactericidal Activity of Macrophages and CD8⁺ T Cell Differentiation.

Hop, Huynh Tan; Huy, Tran Xuan Ngoc; Reyes, Alisha Wehdnesday Bernardo; Arayan, Lauren Togonon; Vu, Son Hai; Min, WonGi; Lee, Hu Jang; Kang, Chang Keun; Kim, Dong Hee; Tark, Dong Seob; Kim, Suk.

Afiliação

Hop HT; Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju, Republic of Korea.
Huy TXN; Biozentrum, University of Basel, Basel, Switzerland.
Reyes AWB; Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju, Republic of Korea.
Arayan LT; Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju, Republic of Korea.
Vu SH; Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju, Republic of Korea.
Min W; Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju, Republic of Korea.
Lee HJ; Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju, Republic of Korea.
Kang CK; Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju, Republic of Korea.
Kim DH; Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju, Republic of Korea.
Tark DS; School of Medicine, Gyeongsang National University, Jinju, Republic of Korea.
Kim S; Korea Zoonosis Research Institute, Chonbuk National University, Iksan, Republic of Korea.

Infect Immun ; 87(11)2019 11.

Article em En | MEDLINE | ID: mdl-31451617

Assuntos

Brucella abortus/fisiologia; Citocinas/metabolismo; Interleucina-6/metabolismo; Macrófagos/microbiologia; Animais; Anticorpos; Células Apresentadoras de Antígenos; Receptor gp130 de Citocina/genética; Receptor gp130 de Citocina/metabolismo; Citocinas/genética; Interleucina-6/genética; Camundongos; Células RAW 264.7; Interferência de RNA; Receptores de Interleucina-6/genética; Receptores de Interleucina-6/metabolismo; Fator de Transcrição STAT1/genética; Fator de Transcrição STAT1/metabolismo; Fator de Transcrição STAT3/genética; Fator de Transcrição STAT3/metabolismo; Transdução de Sinais; Proteína 3 Supressora da Sinalização de Citocinas/genética; Proteína 3 Supressora da Sinalização de Citocinas/metabolismo; Células Th1/metabolismo

Palavras-chave

B. abortus; IL-6; SOCS3; cytotoxic T cells; lysosomal enzymes

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Brucella abortus / Citocinas / Interleucina-6 / Macrófagos Limite: Animals Idioma: En Revista: Infect Immun Ano de publicação: 2019 Tipo de documento: Article País de publicação: Estados Unidos

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