Activated Wnt/ß-Catenin signaling contributes to E3 ubiquitin ligase EDD-conferred docetaxel resistance in prostate cancer.

Bian, Pan; Dou, Zhongling; Jia, Zhaohui; Li, Wensheng; Pan, Dong

Bian, Pan; Dou, Zhongling; Jia, Zhaohui; Li, Wensheng; Pan, Dong.

Afiliação

Bian P; Department of Urology, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, Luoyang 471003, China.
Dou Z; Department of Urology, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, Luoyang 471003, China. Electronic address: d_zling@163.com.
Jia Z; Department of Urology, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, Luoyang 471003, China.
Li W; Department of Urology, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, Luoyang 471003, China.
Pan D; Department of Urology, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, Luoyang 471003, China.

Life Sci ; 254: 116816, 2020 Aug 01.

Article em En | MEDLINE | ID: mdl-31472148

Assuntos

Antineoplásicos/uso terapêutico; Docetaxel/uso terapêutico; Resistencia a Medicamentos Antineoplásicos; Neoplasias da Próstata/tratamento farmacológico; Ubiquitina-Proteína Ligases/metabolismo; Via de Sinalização Wnt/fisiologia; beta Catenina/metabolismo; Animais; Técnicas de Silenciamento de Genes; Humanos; Masculino; Camundongos; Camundongos Endogâmicos NOD; Camundongos SCID; Neoplasias da Próstata/enzimologia; Neoplasias da Próstata/metabolismo; Regulação para Cima; beta Catenina/genética

Palavras-chave

Docetaxel resistance; E3 ubiquitin ligase; EDD; Prostate cancer; Wnt/ß-Catenin signaling

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Resistencia a Medicamentos Antineoplásicos / Ubiquitina-Proteína Ligases / Beta Catenina / Via de Sinalização Wnt / Docetaxel / Antineoplásicos Limite: Animals / Humans / Male Idioma: En Revista: Life Sci Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Holanda

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