RNA-binding protein CELF6 is cell cycle regulated and controls cancer cell proliferation by stabilizing p21.

Liu, Gang; Zhang, Qianwen; Xia, Li; Shi, Mengjuan; Cai, Jin; Zhang, Haowei; Li, Jia; Lin, Guanglan; Xie, Weidong; Zhang, Yaou; Xu, Naihan

Liu, Gang; Zhang, Qianwen; Xia, Li; Shi, Mengjuan; Cai, Jin; Zhang, Haowei; Li, Jia; Lin, Guanglan; Xie, Weidong; Zhang, Yaou; Xu, Naihan.

Afiliação

Liu G; State Key Laboratory of Chemical Oncogenomics, Tsinghua Shenzhen International Graduate School, Tsinghua University, 518055, Shenzhen, China.
Zhang Q; Key Lab in Healthy Science and Technology, Division of Life Science, Tsinghua Shenzhen International Graduate School, Tsinghua University, 518055, Shenzhen, China.
Xia L; State Key Laboratory of Chemical Oncogenomics, Tsinghua Shenzhen International Graduate School, Tsinghua University, 518055, Shenzhen, China.
Shi M; Key Lab in Healthy Science and Technology, Division of Life Science, Tsinghua Shenzhen International Graduate School, Tsinghua University, 518055, Shenzhen, China.
Cai J; State Key Laboratory of Chemical Oncogenomics, Tsinghua Shenzhen International Graduate School, Tsinghua University, 518055, Shenzhen, China.
Zhang H; Key Lab in Healthy Science and Technology, Division of Life Science, Tsinghua Shenzhen International Graduate School, Tsinghua University, 518055, Shenzhen, China.
Li J; State Key Laboratory of Chemical Oncogenomics, Tsinghua Shenzhen International Graduate School, Tsinghua University, 518055, Shenzhen, China.
Lin G; Key Lab in Healthy Science and Technology, Division of Life Science, Tsinghua Shenzhen International Graduate School, Tsinghua University, 518055, Shenzhen, China.
Xie W; Key Lab in Healthy Science and Technology, Division of Life Science, Tsinghua Shenzhen International Graduate School, Tsinghua University, 518055, Shenzhen, China.
Zhang Y; Open FIESTA Center, Tsinghua Shenzhen International Graduate School, Tsinghua University, 518055, Shenzhen, China.
Xu N; Key Lab in Healthy Science and Technology, Division of Life Science, Tsinghua Shenzhen International Graduate School, Tsinghua University, 518055, Shenzhen, China.

Cell Death Dis ; 10(10): 688, 2019 09 18.

Article em En | MEDLINE | ID: mdl-31534127

Assuntos

Proteínas CELF/metabolismo; Inibidor de Quinase Dependente de Ciclina p21/metabolismo; Proteínas CELF/biossíntese; Proteínas CELF/genética; Ciclo Celular/fisiologia; Proliferação de Células/fisiologia; Inibidor de Quinase Dependente de Ciclina p21/genética; Técnicas de Inativação de Genes; Células HCT116; Células HEK293; Humanos; Complexo de Endopeptidases do Proteassoma/metabolismo; Estabilidade Proteica; RNA Mensageiro/genética; RNA Mensageiro/metabolismo; Proteínas Ligases SKP Culina F-Box/metabolismo; Transdução de Sinais; Proteína Supressora de Tumor p53/genética; Proteína Supressora de Tumor p53/metabolismo; Ubiquitina/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidor de Quinase Dependente de Ciclina p21 / Proteínas CELF Limite: Humans Idioma: En Revista: Cell Death Dis Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido

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