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Tankyrase disrupts metabolic homeostasis and promotes tumorigenesis by inhibiting LKB1-AMPK signalling.
Li, Nan; Wang, Yifan; Neri, Shinya; Zhen, Yuanli; Fong, Lon Wolf R; Qiao, Yawei; Li, Xu; Chen, Zhen; Stephan, Clifford; Deng, Weiye; Ye, Rui; Jiang, Wen; Zhang, Shuxing; Yu, Yonghao; Hung, Mien-Chie; Chen, Junjie; Lin, Steven H.
Afiliação
  • Li N; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. nli4@mdanderson.org.
  • Wang Y; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Neri S; The University of Texas Graduate School of Biomedical Sciences Houston, Houston, TX, 77030, USA.
  • Zhen Y; Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX, 75219, USA.
  • Fong LWR; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Qiao Y; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
  • Li X; The University of Texas Graduate School of Biomedical Sciences Houston, Houston, TX, 77030, USA.
  • Chen Z; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Stephan C; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Deng W; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Ye R; School of Life Science, Westlake University, Hangzhou, 310024, China.
  • Jiang W; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Zhang S; Center for Translational Cancer Research, The Institute of Biosciences and Technology at Texas A&M University, Houston, TX, 77030, USA.
  • Yu Y; Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX, 75219, USA.
  • Hung MC; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Chen J; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Lin SH; The University of Texas Graduate School of Biomedical Sciences Houston, Houston, TX, 77030, USA.
Nat Commun ; 10(1): 4363, 2019 09 25.
Article em En | MEDLINE | ID: mdl-31554794
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Serina-Treonina Quinases / Tanquirases / Metabolismo Energético / Inibidores Enzimáticos / Proteínas Quinases Ativadas por AMP / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Serina-Treonina Quinases / Tanquirases / Metabolismo Energético / Inibidores Enzimáticos / Proteínas Quinases Ativadas por AMP / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido