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Akt inhibition synergizes with polycomb repressive complex 2 inhibition in the treatment of multiple myeloma.
Rizk, Mohamed; Rizq, Ola; Oshima, Motohiko; Nakajima-Takagi, Yaeko; Koide, Shuhei; Saraya, Atsunori; Isshiki, Yusuke; Chiba, Tetsuhiro; Yamazaki, Satoshi; Ma, Anqi; Jin, Jian; Iwama, Atsushi; Mimura, Naoya.
Afiliação
  • Rizk M; Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Rizq O; Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Oshima M; Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Nakajima-Takagi Y; Department of Medical Oncology, LeBow Institute for Myeloma Therapeutics and Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Koide S; Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Saraya A; Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Isshiki Y; Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Chiba T; Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Yamazaki S; Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Ma A; Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Jin J; Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Iwama A; Department of Hematology, Chiba University Hospital, Chiba, Japan.
  • Mimura N; Department of Clinical Cell Biology and Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.
Cancer Sci ; 110(12): 3695-3707, 2019 Dec.
Article em En | MEDLINE | ID: mdl-31571328
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas c-akt / Complexo Repressor Polycomb 2 / Compostos Heterocíclicos com 3 Anéis / Mieloma Múltiplo Limite: Humans Idioma: En Revista: Cancer Sci Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Japão País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas c-akt / Complexo Repressor Polycomb 2 / Compostos Heterocíclicos com 3 Anéis / Mieloma Múltiplo Limite: Humans Idioma: En Revista: Cancer Sci Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Japão País de publicação: Reino Unido