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Circulating uromodulin inhibits systemic oxidative stress by inactivating the TRPM2 channel.
LaFavers, Kaice A; Macedo, Etienne; Garimella, Pranav S; Lima, Camila; Khan, Shehnaz; Myslinski, Jered; McClintick, Jeanette; Witzmann, Frank A; Winfree, Seth; Phillips, Carrie L; Hato, Takashi; Dagher, Pierre C; Wu, Xue-Ru; El-Achkar, Tarek M; Micanovic, Radmila.
Afiliação
  • LaFavers KA; Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
  • Macedo E; Division of Nephrology-Hypertension, Department of Medicine, University of California San Diego, San Diego, CA 92093, USA.
  • Garimella PS; Division of Nephrology-Hypertension, Department of Medicine, University of California San Diego, San Diego, CA 92093, USA.
  • Lima C; Division of Nephrology, Department of Medicine, University of Sao Paulo, Sao Paulo 05403, Brazil.
  • Khan S; Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
  • Myslinski J; Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
  • McClintick J; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
  • Witzmann FA; Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
  • Winfree S; Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
  • Phillips CL; Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
  • Hato T; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
  • Dagher PC; Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
  • Wu XR; Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
  • El-Achkar TM; Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
  • Micanovic R; Richard L. Roudebush VA Medical Center, Indianapolis, IN 46202, USA.
Sci Transl Med ; 11(512)2019 10 02.
Article em En | MEDLINE | ID: mdl-31578243

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Canais de Cátion TRPM / Uromodulina Tipo de estudo: Prognostic_studies Limite: Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Canais de Cátion TRPM / Uromodulina Tipo de estudo: Prognostic_studies Limite: Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos