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Safety and efficacy of nivolumab in challenging subgroups with advanced melanoma who progressed on or after ipilimumab treatment: A single-arm, open-label, phase II study (CheckMate 172).
Schadendorf, Dirk; Ascierto, Paolo A; Haanen, John; Espinosa, Enrique; Demidov, Lev; Garbe, Claus; Guida, Michele; Lorigan, Paul; Chiarion-Sileni, Vanna; Gogas, Helen; Maio, Michele; Fierro, Maria Teresa; Hoeller, Christoph; Terheyden, Patrick; Gutzmer, Ralf; Guren, Tormod K; Bafaloukos, Dimitrios; Rutkowski, Piotr; Plummer, Ruth; Waterston, Ashita; Kaatz, Martin; Mandala, Mario; Marquez-Rodas, Ivan; Muñoz-Couselo, Eva; Dummer, Reinhard; Grigoryeva, Elena; Young, Tina C; Nathan, Paul.
Afiliação
  • Schadendorf D; Department of Dermatology, University Hospital Essen, Essen, German Cancer Consortium, Heidelberg, Germany. Electronic address: Dirk.Schadendorf@uk-essen.de.
  • Ascierto PA; Unit of Melanoma, Cancer Immunotherapy and Development Therapeutics, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • Haanen J; Department of Medical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Espinosa E; Department of Medical Oncology, Hospital Universitario La Paz, Universidad Autónoma de Madrid, Madrid, Spain.
  • Demidov L; N.N. Blokhin Russian Cancer Research Centre, Ministry of Health, Moscow, Russia.
  • Garbe C; Division of Dermatologic Oncology, Department of Dermatology, Eberhard Karls University, Tübingen, Germany.
  • Guida M; Department of Medical Oncology, IRCCS Istituto Tumori "Giovanni Paolo II", Bari, Italy.
  • Lorigan P; Institute of Cancer Sciences, University of Manchester, The Christie NHS Foundation Trust, Manchester, UK.
  • Chiarion-Sileni V; Melanoma Oncology Unit, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.
  • Gogas H; First Department of Medicine, National and Kapodistrian University of Athens School of Medicine, Laiko General Hospital, Athens, Greece.
  • Maio M; Division of Medical Oncology and Immunotherapy, Center for Immuno-Oncology, University Hospital of Siena, Siena, Italy.
  • Fierro MT; Department of Medical Sciences, Dermatologic Clinic, University of Turin, Turin, Italy.
  • Hoeller C; Department of Dermatology, Medical University of Vienna, Vienna, Austria.
  • Terheyden P; Department of Dermatology, University of Lübeck, Lübeck, Germany.
  • Gutzmer R; Department of Dermatology, Hannover Medical School, Skin Cancer Centre Hannover, Hannover, Germany.
  • Guren TK; Department of Oncology, Oslo University Hospital, Oslo, Norway.
  • Bafaloukos D; Department of Oncology, Metropolitan Hospital, Athens, Greece.
  • Rutkowski P; Department of Soft Tissue/Bone Sarcoma and Melanoma, Maria Sklodowska-Curie Institute, Oncology Center, Warsaw, Poland.
  • Plummer R; Northern Institute for Cancer Research, Newcastle University, Newcastle Upon Tyne, United Kingdom.
  • Waterston A; Clinical Trials Unit, Beatson West of Scotland Cancer Centre, Glasgow, UK.
  • Kaatz M; Department of Dermatology, SRH Wald Clinics, University Hospital, Gera, Germany.
  • Mandala M; Unit of Medical Oncology, Department of Oncology & Hematology, Papa Giovanni XXIII Hospital, Bergamo, Italy.
  • Marquez-Rodas I; Medical Oncology Department, General University Hospital, Gregorio Marañón and CIBERONC, Madrid, Spain.
  • Muñoz-Couselo E; Medical Oncology, Vall D'Hebron University, Barcelona, Spain.
  • Dummer R; Department of Dermatology, Universitats Spital, Zürich, Switzerland.
  • Grigoryeva E; Oncology Clinical Development, Bristol-Myers Squibb, Princeton, NJ, USA.
  • Young TC; Global Biometric Sciences, Bristol-Myers Squibb, Princeton, NJ, USA.
  • Nathan P; Department of Medical Oncology, Mount Vernon Cancer Centre, London, United Kingdom.
Eur J Cancer ; 121: 144-153, 2019 11.
Article em En | MEDLINE | ID: mdl-31581055
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Ipilimumab / Nivolumabe / Melanoma Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Eur J Cancer Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Ipilimumab / Nivolumabe / Melanoma Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Eur J Cancer Ano de publicação: 2019 Tipo de documento: Article