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CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation.
Cheng, Weiwei; Wang, Shaopeng; Zhang, Zhe; Morgens, David W; Hayes, Lindsey R; Lee, Soojin; Portz, Bede; Xie, Yongzhi; Nguyen, Baotram V; Haney, Michael S; Yan, Shirui; Dong, Daoyuan; Coyne, Alyssa N; Yang, Junhua; Xian, Fengfan; Cleveland, Don W; Qiu, Zhaozhu; Rothstein, Jeffrey D; Shorter, James; Gao, Fen-Biao; Bassik, Michael C; Sun, Shuying.
Afiliação
  • Cheng W; Department of Pathology and Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Wang S; Department of Pathology and Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Zhang Z; Department of Pathology and Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Morgens DW; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Hayes LR; Brain Science Institute and Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Lee S; Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Portz B; Department of Biochemistry and Biophysics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Xie Y; Department of Pathology and Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Nguyen BV; Department of Biochemistry and Biophysics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Haney MS; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Yan S; Department of Pathology and Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Dong D; Department of Pathology and Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Coyne AN; Brain Science Institute and Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Yang J; Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Xian F; Department of Pathology and Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Cleveland DW; Ludwig Institute for Cancer Research and Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA 92093, USA.
  • Qiu Z; Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Rothstein JD; Brain Science Institute and Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Shorter J; Department of Biochemistry and Biophysics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Gao FB; Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Bassik MC; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Sun S; Department of Pathology and Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Electronic address: shuying.sun@jhmi.edu.
Neuron ; 104(5): 885-898.e8, 2019 12 04.
Article em En | MEDLINE | ID: mdl-31587919
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA Helicases DEAD-box / Demência Frontotemporal / Proteína C9orf72 / Esclerose Lateral Amiotrófica Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Neuron Assunto da revista: NEUROLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA Helicases DEAD-box / Demência Frontotemporal / Proteína C9orf72 / Esclerose Lateral Amiotrófica Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Neuron Assunto da revista: NEUROLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos