LncRNA SNHG3 is activated by E2F1 and promotes proliferation and migration of non-small-cell lung cancer cells through activating TGF-ß pathway and IL-6/JAK2/STAT3 pathway.

Shi, Jindong; Li, Jiannan; Yang, Shuang; Hu, Xiaoying; Chen, Jiajun; Feng, Jingjing; Shi, Tianyun; He, Yanchao; Mei, Zhoufang; He, Wei; Xie, Juan; Li, Shanqun; Jie, Zhijun; Tu, Shuiping

Shi, Jindong; Li, Jiannan; Yang, Shuang; Hu, Xiaoying; Chen, Jiajun; Feng, Jingjing; Shi, Tianyun; He, Yanchao; Mei, Zhoufang; He, Wei; Xie, Juan; Li, Shanqun; Jie, Zhijun; Tu, Shuiping.

Afiliação

Shi J; Department of Respiratory Medicine, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China.
Li J; Department of Respiratory Medicine, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China.
Yang S; General Department, Jiangchuan Community Healthcare Service Center, Shanghai, China.
Hu X; General Department, Jiangchuan Community Healthcare Service Center, Shanghai, China.
Chen J; Department of Respiratory Medicine, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China.
Feng J; Department of Respiratory Medicine, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China.
Shi T; Department of Respiratory Medicine, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China.
He Y; Department of Respiratory Medicine, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China.
Mei Z; Department of Respiratory Medicine, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China.
He W; Department of Respiratory Medicine, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China.
Xie J; Department of Respiratory Medicine, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China.
Li S; Department of Respiratory Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Jie Z; Department of Respiratory Medicine, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China.
Tu S; Department of Oncology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

J Cell Physiol ; 235(3): 2891-2900, 2020 03.

Article em En | MEDLINE | ID: mdl-31602642

Assuntos

Fator de Transcrição E2F1/metabolismo; RNA Longo não Codificante/genética; Transdução de Sinais/genética; Fator de Crescimento Transformador beta/metabolismo; Animais; Carcinoma Pulmonar de Células não Pequenas/genética; Linhagem Celular Tumoral; Proliferação de Células/genética; Fator de Transcrição E2F1/genética; Transição Epitelial-Mesenquimal/genética; Regulação Neoplásica da Expressão Gênica/genética; Humanos; Interleucina-6/metabolismo; Janus Quinase 2/metabolismo; Neoplasias Pulmonares/genética; Camundongos; Fator de Transcrição STAT3/genética; Fator de Transcrição STAT3/metabolismo; Regulação para Cima

Palavras-chave

E2F1; IL-6/JAK2/STAT3 pathway; NSCLC; SNHG3; TGF-ß pathway; migration; proliferation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Fator de Crescimento Transformador beta / Fator de Transcrição E2F1 / RNA Longo não Codificante Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Cell Physiol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos

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