[16S rRNA sequence analysis: application and pitfalls]. / 16S-rRNA-sequentieanalyse.
Ned Tijdschr Geneeskd
; 1632019 10 10.
Article
em Nl
| MEDLINE
| ID: mdl-31609564
ABSTRACT
16S rRNA gene sequencing is a useful tool for identification of non-cultured or hard-to-identify bacteria. This technique can be used to detect and identify bacteria in clinical materials, such as cerebrospinal fluid and heart valves, if conventional methods do not reveal pathogens. A major advantage compared with other techniques is that it is not necessary to know in advance what pathogen is the likely cause of the disease. An important drawback is the background noise generated by traces of bacterial DNA in reagents.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Bactérias
/
DNA Bacteriano
/
RNA Ribossômico 16S
Limite:
Humans
Idioma:
Nl
Revista:
Ned Tijdschr Geneeskd
Ano de publicação:
2019
Tipo de documento:
Article