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The PedBE clock accurately estimates DNA methylation age in pediatric buccal cells.
McEwen, Lisa M; O'Donnell, Kieran J; McGill, Megan G; Edgar, Rachel D; Jones, Meaghan J; MacIsaac, Julia L; Lin, David Tse Shen; Ramadori, Katia; Morin, Alexander; Gladish, Nicole; Garg, Elika; Unternaehrer, Eva; Pokhvisneva, Irina; Karnani, Neerja; Kee, Michelle Z L; Klengel, Torsten; Adler, Nancy E; Barr, Ronald G; Letourneau, Nicole; Giesbrecht, Gerald F; Reynolds, James N; Czamara, Darina; Armstrong, Jeffrey M; Essex, Marilyn J; de Weerth, Carolina; Beijers, Roseriet; Tollenaar, Marieke S; Bradley, Bekh; Jovanovic, Tanja; Ressler, Kerry J; Steiner, Meir; Entringer, Sonja; Wadhwa, Pathik D; Buss, Claudia; Bush, Nicole R; Binder, Elisabeth B; Boyce, W Thomas; Meaney, Michael J; Horvath, Steve; Kobor, Michael S.
Afiliação
  • McEwen LM; Department of Medical Genetics, University of British Columbia-BC Children's Hospital Research Institute, Vancouver, BC, Canada V5Z 4H4.
  • O'Donnell KJ; Douglas Mental Health University Institute, McGill University, Montreal, QC, Canada H4H 1R3.
  • McGill MG; Child and Brain Development Program, Canadian Institute for Advanced Research (CIFAR) Institute, Toronto, ON, Canada M5G 1M1.
  • Edgar RD; Douglas Mental Health University Institute, McGill University, Montreal, QC, Canada H4H 1R3.
  • Jones MJ; Department of Medical Genetics, University of British Columbia-BC Children's Hospital Research Institute, Vancouver, BC, Canada V5Z 4H4.
  • MacIsaac JL; Department of Medical Genetics, University of British Columbia-BC Children's Hospital Research Institute, Vancouver, BC, Canada V5Z 4H4.
  • Lin DTS; Department of Medical Genetics, University of British Columbia-BC Children's Hospital Research Institute, Vancouver, BC, Canada V5Z 4H4.
  • Ramadori K; Department of Medical Genetics, University of British Columbia-BC Children's Hospital Research Institute, Vancouver, BC, Canada V5Z 4H4.
  • Morin A; Department of Medical Genetics, University of British Columbia-BC Children's Hospital Research Institute, Vancouver, BC, Canada V5Z 4H4.
  • Gladish N; Department of Medical Genetics, University of British Columbia-BC Children's Hospital Research Institute, Vancouver, BC, Canada V5Z 4H4.
  • Garg E; Department of Medical Genetics, University of British Columbia-BC Children's Hospital Research Institute, Vancouver, BC, Canada V5Z 4H4.
  • Unternaehrer E; Douglas Mental Health University Institute, McGill University, Montreal, QC, Canada H4H 1R3.
  • Pokhvisneva I; Douglas Mental Health University Institute, McGill University, Montreal, QC, Canada H4H 1R3.
  • Karnani N; Douglas Mental Health University Institute, McGill University, Montreal, QC, Canada H4H 1R3.
  • Kee MZL; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR); Singapore 117609.
  • Klengel T; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117596.
  • Adler NE; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR); Singapore 117609.
  • Barr RG; Department of Psychiatry, Harvard Medical School-McLean Hospital, Belmont, MA 02478.
  • Letourneau N; Child and Brain Development Program, Canadian Institute for Advanced Research (CIFAR) Institute, Toronto, ON, Canada M5G 1M1.
  • Giesbrecht GF; Department of Psychiatry, University of California, San Francisco, CA 94143.
  • Reynolds JN; Department of Pediatrics, University of California, San Francisco, CA 94143.
  • Czamara D; Child and Brain Development Program, Canadian Institute for Advanced Research (CIFAR) Institute, Toronto, ON, Canada M5G 1M1.
  • Armstrong JM; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada V6T 1Z4.
  • Essex MJ; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB, Canada T2N 4N1.
  • de Weerth C; Faculty of Nursing, University of Calgary, Calgary, AB, Canada T2N 1N4.
  • Beijers R; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB, Canada T2N 4N1.
  • Tollenaar MS; Department of Paediatrics, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada T2N 1N4.
  • Bradley B; Department of Biomedical and Molecular Sciences, School of Medicine, Queen's University, Kingston, ON, Canada K7L 3N6.
  • Jovanovic T; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, 80804 Munich, Germany.
  • Ressler KJ; Department of Psychiatry, University of Wisconsin-Madison, Madison, WI 53706.
  • Steiner M; Department of Psychiatry, University of Wisconsin-Madison, Madison, WI 53706.
  • Entringer S; Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, 6525 HR, Nijmegen, The Netherlands.
  • Wadhwa PD; Behavioural Science Institute, Radboud University, 6525 HR, Nijmegen, The Netherlands.
  • Buss C; Leiden Institute for Brain and Cognition, Institute of Psychology, Leiden University, 2300 RB, Leiden, The Netherlands.
  • Bush NR; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30322.
  • Binder EB; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30322.
  • Boyce WT; Department of Psychiatry, Harvard Medical School-McLean Hospital, Belmont, MA 02478.
  • Meaney MJ; Department of Psychiatry and Behavioural Neurosciences, St. Joseph's Healthcare Hamilton, McMaster University, Hamilton, ON, Canada L8S 4L8.
  • Horvath S; Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Institute of Medical Psychology, 10117 Berlin, Germany.
  • Kobor MS; Development, Health, and Disease Research Program, University of California, Irvine, CA 92617.
Proc Natl Acad Sci U S A ; 117(38): 23329-23335, 2020 09 22.
Article em En | MEDLINE | ID: mdl-31611402
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Epiteliais / Epigenômica / Mucosa Bucal Tipo de estudo: Etiology_studies / Evaluation_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Epiteliais / Epigenômica / Mucosa Bucal Tipo de estudo: Etiology_studies / Evaluation_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos