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Impaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients.
Nickels, Sarah Louise; Walter, Jonas; Bolognin, Silvia; Gérard, Deborah; Jaeger, Christian; Qing, Xiaobing; Tisserand, Johan; Jarazo, Javier; Hemmer, Kathrin; Harms, Amy; Halder, Rashi; Lucarelli, Philippe; Berger, Emanuel; Antony, Paul M A; Glaab, Enrico; Hankemeier, Thomas; Klein, Christine; Sauter, Thomas; Sinkkonen, Lasse; Schwamborn, Jens Christian.
Afiliação
  • Nickels SL; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, L-4367, Belvaux, Luxembourg; Life Sciences Research Unit (LSRU), Systems Biology Group, University of Luxembourg, L-4367, Belvaux, Luxembourg; Integrated Biobank of Luxembourg (IBBL), Luxembourg Institute of Health, L-3555,
  • Walter J; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, L-4367, Belvaux, Luxembourg.
  • Bolognin S; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, L-4367, Belvaux, Luxembourg.
  • Gérard D; Life Sciences Research Unit (LSRU), Systems Biology Group, University of Luxembourg, L-4367, Belvaux, Luxembourg.
  • Jaeger C; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, L-4367, Belvaux, Luxembourg.
  • Qing X; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, L-4367, Belvaux, Luxembourg.
  • Tisserand J; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, L-4367, Belvaux, Luxembourg.
  • Jarazo J; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, L-4367, Belvaux, Luxembourg.
  • Hemmer K; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, L-4367, Belvaux, Luxembourg.
  • Harms A; Leiden Academic Centre for Drug Research (LACDR), Analytical Biosciences, Leiden University, NL-2333, CC Leiden, Netherlands.
  • Halder R; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, L-4367, Belvaux, Luxembourg.
  • Lucarelli P; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, L-4367, Belvaux, Luxembourg.
  • Berger E; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, L-4367, Belvaux, Luxembourg.
  • Antony PMA; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, L-4367, Belvaux, Luxembourg.
  • Glaab E; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, L-4367, Belvaux, Luxembourg.
  • Hankemeier T; Leiden Academic Centre for Drug Research (LACDR), Analytical Biosciences, Leiden University, NL-2333, CC Leiden, Netherlands.
  • Klein C; Institute of Neurogenetics, University of Lübeck, D-23538, Lübeck, Germany.
  • Sauter T; Life Sciences Research Unit (LSRU), Systems Biology Group, University of Luxembourg, L-4367, Belvaux, Luxembourg.
  • Sinkkonen L; Life Sciences Research Unit (LSRU), Systems Biology Group, University of Luxembourg, L-4367, Belvaux, Luxembourg.
  • Schwamborn JC; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, L-4367, Belvaux, Luxembourg. Electronic address: jens.schwamborn@uni.lu.
Parkinsonism Relat Disord ; 67: 48-55, 2019 10.
Article em En | MEDLINE | ID: mdl-31621607

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Serina / Racemases e Epimerases / Autorrenovação Celular Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Parkinsonism Relat Disord Assunto da revista: NEUROLOGIA Ano de publicação: 2019 Tipo de documento: Article País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Serina / Racemases e Epimerases / Autorrenovação Celular Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Parkinsonism Relat Disord Assunto da revista: NEUROLOGIA Ano de publicação: 2019 Tipo de documento: Article País de publicação: Reino Unido