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Hypermethylation of FOXA1 and allelic loss of PTEN drive squamous differentiation and promote heterogeneity in bladder cancer.
Osei-Amponsa, Vasty; Buckwalter, Jenna M; Shuman, Lauren; Zheng, Zongyu; Yamashita, Hironobu; Walter, Vonn; Wildermuth, Thomas; Ellis-Mohl, Justine; Liu, Chang; Warrick, Joshua I; Shantz, Lisa M; Feehan, Robert P; Al-Ahmadie, Hikmat; Mendelsohn, Cathy; Raman, Jay D; Kaestner, Klaus H; Wu, Xue-Ru; DeGraff, David J.
Afiliação
  • Osei-Amponsa V; Department of Pathology and Laboratory Medicine, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Buckwalter JM; Department of Pathology and Laboratory Medicine, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Shuman L; Department of Surgery, Division of Urology, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Zheng Z; Department of Pathology and Laboratory Medicine, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Yamashita H; Department of Surgery, Division of Urology, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Walter V; Department of Pathology and Laboratory Medicine, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Wildermuth T; Department of Pathology and Laboratory Medicine, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Ellis-Mohl J; Department of Surgery, Division of Urology, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Liu C; Department of Public Health Sciences, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Warrick JI; Department of Pathology and Laboratory Medicine, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Shantz LM; Department of Surgery, Division of Urology, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Feehan RP; Department of Pathology and Laboratory Medicine, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Al-Ahmadie H; Department of Surgery, Division of Urology, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Mendelsohn C; Department of Urology, Columbia University, New York, NY, USA.
  • Raman JD; Department of Pathology and Laboratory Medicine, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Kaestner KH; Department of Surgery, Division of Urology, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Wu XR; Department of Cellular and Molecular Physiology, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • DeGraff DJ; Department of Cellular and Molecular Physiology, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
Oncogene ; 39(6): 1302-1317, 2020 02.
Article em En | MEDLINE | ID: mdl-31636388

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Bexiga Urinária / Carcinoma de Células Escamosas / Diferenciação Celular / Metilação de DNA / Perda de Heterozigosidade / PTEN Fosfo-Hidrolase / Fator 3-alfa Nuclear de Hepatócito Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Oncogene Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Bexiga Urinária / Carcinoma de Células Escamosas / Diferenciação Celular / Metilação de DNA / Perda de Heterozigosidade / PTEN Fosfo-Hidrolase / Fator 3-alfa Nuclear de Hepatócito Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Oncogene Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido