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Synthesis of 2-arylhydrazinylidene-3-oxo-4,4,4-trifluorobutanoic acids as new selective carboxylesterase inhibitors and radical scavengers.
Khudina, Olga G; Makhaeva, Galina F; Elkina, Natalia A; Boltneva, Natalia P; Serebryakova, Olga G; Shchegolkov, Evgeny V; Rudakova, Elena V; Lushchekina, Sofya V; Burgart, Yanina V; Bachurin, Sergey O; Richardson, Rudy J; Saloutin, Victor I.
Afiliação
  • Khudina OG; Postovsky Institute of Organic Synthesis, Ural Branch of Russian Academy of Sciences, Ekaterinburg 620990, Russia.
  • Makhaeva GF; Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka 142432, Russia.
  • Elkina NA; Postovsky Institute of Organic Synthesis, Ural Branch of Russian Academy of Sciences, Ekaterinburg 620990, Russia.
  • Boltneva NP; Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka 142432, Russia.
  • Serebryakova OG; Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka 142432, Russia.
  • Shchegolkov EV; Postovsky Institute of Organic Synthesis, Ural Branch of Russian Academy of Sciences, Ekaterinburg 620990, Russia; Ural Federal University Named After the First President of Russia B.N. Yeltsin, Ekaterinburg 620002, Russia.
  • Rudakova EV; Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka 142432, Russia.
  • Lushchekina SV; Emanuel Institute of Biochemical Physics Russian Academy of Sciences, Moscow 119334, Russia.
  • Burgart YV; Postovsky Institute of Organic Synthesis, Ural Branch of Russian Academy of Sciences, Ekaterinburg 620990, Russia; Ural Federal University Named After the First President of Russia B.N. Yeltsin, Ekaterinburg 620002, Russia.
  • Bachurin SO; Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka 142432, Russia.
  • Richardson RJ; Departments of Environmental Health Sciences and Neurology, University of Michigan, Ann Arbor, MI 48109, USA; Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: rjrich@umich.edu.
  • Saloutin VI; Postovsky Institute of Organic Synthesis, Ural Branch of Russian Academy of Sciences, Ekaterinburg 620990, Russia; Ural Federal University Named After the First President of Russia B.N. Yeltsin, Ekaterinburg 620002, Russia.
Bioorg Med Chem Lett ; 29(23): 126716, 2019 12 01.
Article em En | MEDLINE | ID: mdl-31640885
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carboxilesterase / Simulação de Acoplamento Molecular / Antioxidantes Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Federação Russa País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carboxilesterase / Simulação de Acoplamento Molecular / Antioxidantes Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Federação Russa País de publicação: Reino Unido