L-DOPA causes mitochondrial dysfunction in vitro: A novel mechanism of L-DOPA toxicity uncovered.

Giannopoulos, Steven; Samardzic, Kate; Raymond, Benjamin B A; Djordjevic, Steven P; Rodgers, Kenneth J

Giannopoulos, Steven; Samardzic, Kate; Raymond, Benjamin B A; Djordjevic, Steven P; Rodgers, Kenneth J.

Afiliação

Giannopoulos S; Neurotoxin Research Group, School of Life Sciences, Faculty of Science, University of Technology Sydney, Australia.
Samardzic K; Neurotoxin Research Group, School of Life Sciences, Faculty of Science, University of Technology Sydney, Australia.
Raymond BBA; I3 institute, School of Life Sciences, Faculty of Science, University of Technology Sydney, Australia.
Djordjevic SP; I3 institute, School of Life Sciences, Faculty of Science, University of Technology Sydney, Australia.
Rodgers KJ; Neurotoxin Research Group, School of Life Sciences, Faculty of Science, University of Technology Sydney, Australia. Electronic address: kenneth.rodgers@uts.edu.au.

Int J Biochem Cell Biol ; 117: 105624, 2019 12.

Article em En | MEDLINE | ID: mdl-31654750

Assuntos

Levodopa/toxicidade; Mitocôndrias/patologia; Doença de Parkinson/tratamento farmacológico; Humanos; Levodopa/farmacologia

Palavras-chave

L-dopa; Mitochondrial dysfunction; Non-protein amino acid; Parkinson's disease

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Levodopa / Mitocôndrias Tipo de estudo: Etiology_studies Limite: Humans Idioma: En Revista: Int J Biochem Cell Biol Assunto da revista: BIOQUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Austrália País de publicação: Holanda

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