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Multiple-Ascending-Dose Phase 1 Clinical Study of the Safety, Tolerability, and Pharmacokinetics of CRS3123, a Narrow-Spectrum Agent with Minimal Disruption of Normal Gut Microbiota.
Lomeli, Barbara K; Galbraith, Hal; Schettler, Jared; Saviolakis, George A; El-Amin, Wael; Osborn, Blaire; Ravel, Jacques; Hazleton, Keith; Lozupone, Catherine A; Evans, Ronald J; Bell, Stacie J; Ochsner, Urs A; Jarvis, Thale C; Baqar, Shahida; Janjic, Nebojsa.
Afiliação
  • Lomeli BK; Quintiles Phase One Services, Overland Park, Kansas, USA.
  • Galbraith H; Quintiles Phase One Services, Overland Park, Kansas, USA.
  • Schettler J; Quintiles Phase One Services, Overland Park, Kansas, USA.
  • Saviolakis GA; DynPort Vaccine Company LLC, Frederick, Maryland, USA.
  • El-Amin W; DynPort Vaccine Company LLC, Frederick, Maryland, USA.
  • Osborn B; Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Ravel J; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
  • Hazleton K; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.
  • Lozupone CA; Division of Pediatric Gastroenterology, Hepatology and Nutrition, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
  • Evans RJ; Division of Biomedical Informatics and Personalized Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
  • Bell SJ; Crestone, Inc., Boulder, Colorado, USA.
  • Ochsner UA; Crestone, Inc., Boulder, Colorado, USA.
  • Jarvis TC; Crestone, Inc., Boulder, Colorado, USA.
  • Baqar S; Crestone, Inc., Boulder, Colorado, USA tjarvis@crestonepharma.com njanjic@crestonepharma.com.
  • Janjic N; Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Antimicrob Agents Chemother ; 64(1)2019 12 20.
Article em En | MEDLINE | ID: mdl-31685472
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiofenos / Benzopiranos / Clostridioides difficile / Microbioma Gastrointestinal / Antibacterianos Tipo de estudo: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiofenos / Benzopiranos / Clostridioides difficile / Microbioma Gastrointestinal / Antibacterianos Tipo de estudo: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos