Identification of the circRNA-miRNA-mRNA regulatory network of Hsp90 inhibitor-induced cell death in colorectal cancer by integrated analysis.

Liu, Kaisheng; Guo, Yaomin; Zheng, Kai; Zou, Chang; Wu, Haixiong; Wang, Shaoxiang; Ou, Ling; Wang, Yifei; Huang, Bowan; Wang, Xiao

Liu, Kaisheng; Guo, Yaomin; Zheng, Kai; Zou, Chang; Wu, Haixiong; Wang, Shaoxiang; Ou, Ling; Wang, Yifei; Huang, Bowan; Wang, Xiao.

Afiliação

Liu K; The First Affiliated Hospital of Southern University of Science and Technology, The Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Shenzhen 518020, Guangdong, China.
Guo Y; The First Affiliated Hospital of Southern University of Science and Technology, The Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Shenzhen 518020, Guangdong, China.
Zheng K; School of Pharmaceutical Sciences, Shenzhen University Health Science Center, Shenzhen 518060, Guangdong, China.
Zou C; The First Affiliated Hospital of Southern University of Science and Technology, The Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Shenzhen 518020, Guangdong, China.
Wu H; The First Affiliated Hospital of Southern University of Science and Technology, The Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Shenzhen 518020, Guangdong, China.
Wang S; School of Pharmaceutical Sciences, Shenzhen University Health Science Center, Shenzhen 518060, Guangdong, China.
Ou L; The First Affiliated Hospital of Southern University of Science and Technology, The Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Shenzhen 518020, Guangdong, China.
Wang Y; Institute of Biomedicine, College of Life Science and Technology, Jinan University, Guangzhou 510632, Guangdong, China.
Huang B; Department of Anesthesiology, Central People's Hospital of Zhanjiang, Zhanjiang 524000, Guangdong, China. Electronic address: bowanhuang@126.com.
Wang X; The First Affiliated Hospital of Southern University of Science and Technology, The Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Shenzhen 518020, Guangdong, China. Electronic address: wangxiao0719@163.com.

Gene ; 727: 144232, 2020 Feb 15.

Article em En | MEDLINE | ID: mdl-31715300

Assuntos

Neoplasias Colorretais/genética; Redes Reguladoras de Genes/genética; Células CACO-2; Neoplasias do Colo/genética; Neoplasias Colorretais/metabolismo; Regulação para Baixo; Perfilação da Expressão Gênica; Regulação Neoplásica da Expressão Gênica; Ontologia Genética; Proteínas de Choque Térmico HSP90/antagonistas & inibidores; Proteínas de Choque Térmico HSP90/genética; Compostos Heterocíclicos de 4 ou mais Anéis/farmacologia; Humanos; MicroRNAs/genética; Análise de Sequência com Séries de Oligonucleotídeos; RNA/genética; RNA/metabolismo; RNA Circular/genética; RNA Mensageiro/genética; Reação em Cadeia da Polimerase em Tempo Real; Regulação para Cima

Palavras-chave

Cell death; Colorectal cancer; SNX-2112; circRNA; mRNA; miRNA

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Redes Reguladoras de Genes Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Gene Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Holanda

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