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Synthesis, biological evaluation, and molecular modelling of new naphthalene-chalcone derivatives as potential anticancer agents on MCF-7 breast cancer cells by targeting tubulin colchicine binding site.
Wang, Guangcheng; Liu, Wenjing; Gong, Zipeng; Huang, Yong; Li, Yongjun; Peng, Zhiyun.
Afiliação
  • Wang G; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Provincial Key Laboratory of Pharmaceutics, Guizhou Medical University, Guiyang, China.
  • Liu W; College of Chemistry and Chemical Engineering, Jishou University, Jishou, China.
  • Gong Z; Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University, Guiyang, China.
  • Huang Y; School of Pharmacy, Guizhou Medical University, Guiyang, China.
  • Li Y; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Provincial Key Laboratory of Pharmaceutics, Guizhou Medical University, Guiyang, China.
  • Peng Z; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Provincial Key Laboratory of Pharmaceutics, Guizhou Medical University, Guiyang, China.
J Enzyme Inhib Med Chem ; 35(1): 139-144, 2020 Dec.
Article em En | MEDLINE | ID: mdl-31724435

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tubulina (Proteína) / Neoplasias da Mama / Chalconas / Moduladores de Tubulina / Naftalenos / Antineoplásicos Limite: Female / Humans Idioma: En Revista: J Enzyme Inhib Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tubulina (Proteína) / Neoplasias da Mama / Chalconas / Moduladores de Tubulina / Naftalenos / Antineoplásicos Limite: Female / Humans Idioma: En Revista: J Enzyme Inhib Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido