Encapsulation in Polymeric Nanoparticles Enhances the Enzymatic Stability and the Permeability of the GLP-1 Analog, Liraglutide, Across a Culture Model of Intestinal Permeability.

Ismail, Ruba; Bocsik, Alexandra; Katona, Gábor; Gróf, Ilona; Deli, Mária A; Csóka, Ildikó

Ismail, Ruba; Bocsik, Alexandra; Katona, Gábor; Gróf, Ilona; Deli, Mária A; Csóka, Ildikó.

Afiliação

Ismail R; Institute of Pharmaceutical Technology and Regulatory Affairs, Faculty of Pharmacy, University of Szeged, H-6720 Szeged, Hungary.
Bocsik A; Institute of Biophysics, Biological Research Centre H-6726 Szeged, Hungary.
Katona G; Institute of Pharmaceutical Technology and Regulatory Affairs, Faculty of Pharmacy, University of Szeged, H-6720 Szeged, Hungary.
Gróf I; Institute of Biophysics, Biological Research Centre H-6726 Szeged, Hungary.
Deli MA; Doctoral School of Biology, University of Szeged, H-6726 Szeged, Hungary.
Csóka I; Institute of Biophysics, Biological Research Centre H-6726 Szeged, Hungary.

Pharmaceutics ; 11(11)2019 Nov 12.

Article em En | MEDLINE | ID: mdl-31726699

Palavras-chave

Caco-2 cells; GLP-1 analog; PLGA nanoparticles; enzymatic barrier; intestinal permeability; liraglutide; oral peptide delivery

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Pharmaceutics Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Hungria

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