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Hypoxia-inducible factor 1 (HIF-1) is a new therapeutic target in JAK2V617F-positive myeloproliferative neoplasms.
Baumeister, Julian; Chatain, Nicolas; Hubrich, Annika; Maié, Tiago; Costa, Ivan G; Denecke, Bernd; Han, Lijuan; Küstermann, Caroline; Sontag, Stephanie; Seré, Kristin; Strathmann, Klaus; Zenke, Martin; Schuppert, Andreas; Brümmendorf, Tim H; Kranc, Kamil R; Koschmieder, Steffen; Gezer, Deniz.
Afiliação
  • Baumeister J; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
  • Chatain N; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
  • Hubrich A; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
  • Maié T; Joint Research Center for Computational Biomedicine, RWTH Aachen University, Aachen, Germany.
  • Costa IG; Joint Research Center for Computational Biomedicine, RWTH Aachen University, Aachen, Germany.
  • Denecke B; Interdisciplinary Center for Clinical Research Aachen, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
  • Han L; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
  • Küstermann C; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
  • Sontag S; Institute of Biomedical Engineering, Department of Cell Biology, RWTH Aachen University Medical School, Aachen, Germany; Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.
  • Seré K; Institute of Biomedical Engineering, Department of Cell Biology, RWTH Aachen University Medical School, Aachen, Germany; Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.
  • Strathmann K; Institute of Biomedical Engineering, Department of Cell Biology, RWTH Aachen University Medical School, Aachen, Germany; Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.
  • Zenke M; Institute for Transfusion Medicine, RWTH Aachen University Medical School, Aachen, Germany.
  • Schuppert A; Institute of Biomedical Engineering, Department of Cell Biology, RWTH Aachen University Medical School, Aachen, Germany; Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.
  • Brümmendorf TH; Joint Research Center for Computational Biomedicine, RWTH Aachen University, Aachen, Germany.
  • Kranc KR; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
  • Koschmieder S; Laboratory of Haematopoietic Stem Cell & Leukaemia Biology, Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, UK.
  • Gezer D; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Leukemia ; 34(4): 1062-1074, 2020 04.
Article em En | MEDLINE | ID: mdl-31728053
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biomarcadores Tumorais / Equinomicina / Subunidade alfa do Fator 1 Induzível por Hipóxia / Janus Quinase 2 / Células-Tronco Pluripotentes Induzidas / Mutação / Transtornos Mieloproliferativos Tipo de estudo: Observational_studies / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Leukemia Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biomarcadores Tumorais / Equinomicina / Subunidade alfa do Fator 1 Induzível por Hipóxia / Janus Quinase 2 / Células-Tronco Pluripotentes Induzidas / Mutação / Transtornos Mieloproliferativos Tipo de estudo: Observational_studies / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Leukemia Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Reino Unido