Lipoxin A4 attenuates hyperoxia­induced lung epithelial cell injury via the upregulation of heme oxygenase­1 and inhibition of proinflammatory cytokines.

Luo, Yan-Yan; Wu, Sheng-Hua; Lu, Hong-Yan; Li, Bing-Jie; Li, Shu-Jun; Sun, Zhong-Yi; Jin, Rui; Chen, Xiao-Qing

Lipoxin A4 attenuates hyperoxiainduced lung epithelial cell injury via the upregulation of heme oxygenase1 and inhibition of proinflammatory cytokines.

Luo, Yan-Yan; Wu, Sheng-Hua; Lu, Hong-Yan; Li, Bing-Jie; Li, Shu-Jun; Sun, Zhong-Yi; Jin, Rui; Chen, Xiao-Qing.

Afiliação

Luo YY; Department of Pediatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Wu SH; Department of Pediatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Lu HY; Department of Pediatrics, The Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212000, P.R. China.
Li BJ; Department of Pediatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Li SJ; Department of Pediatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Sun ZY; Department of Pediatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Jin R; Department of Pediatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Chen XQ; Department of Pediatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.

Mol Med Rep ; 21(1): 429-437, 2020 01.

Article em En | MEDLINE | ID: mdl-31746387

Assuntos

Quimiocina CCL2/genética; Heme Oxigenase-1/genética; Lipoxinas/genética; Lesão Pulmonar/genética; Animais; Proliferação de Células/genética; Sobrevivência Celular/genética; Citocinas/genética; Células Epiteliais/metabolismo; Células Epiteliais/patologia; Regulação da Expressão Gênica/genética; Humanos; Interleucina-6/genética; Lesão Pulmonar/patologia; Sistema de Sinalização das MAP Quinases/genética; Camundongos; Proteínas Proto-Oncogênicas c-akt/genética

Palavras-chave

lipoxin a4; hyperoxia; monocyte chemotactic protein 1; interleukin 6; heme oxygenase-1

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quimiocina CCL2 / Lipoxinas / Heme Oxigenase-1 / Lesão Pulmonar Limite: Animals / Humans Idioma: En Revista: Mol Med Rep Ano de publicação: 2020 Tipo de documento: Article País de publicação: Grécia

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