Clinical remission of a treatment-refractory individual with severe repetitive rituals and rumination.
Asian J Psychiatr
; 47: 101878, 2020 Jan.
Article
em En
| MEDLINE
| ID: mdl-31756555
ABSTRACT
BACKGROUND:
Obsessive-compulsive disorder (OCD) is a severe chronic mental disorder and tends to be refractory to pharmacotherapy or psychotherapy. For treatment-refractory patients, neurosurgical interventions are options. 64 % of OCD patients who undergo neurosurgery still have greater than 16 in the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) after a long-term follow-up. Here, we reported a patient living with long-term OCD (20 years) who was refractory to pharmacotherapy, mindfulness-based psychotherapy, and neurosurgery that injured his bilateral anterior cingulates (AC) and caudate nucleus.METHODS:
The patient accepted a novel psychotherapy named cognitive-coping therapy (CCT) and completed Y-BOCS, Hamilton depression rating scale, the Hamilton anxiety rating scale, social and occupational function assessment, and resting-state function magnetic resonance imaging scans (rs-fMRI) before and after 4-week CCT.RESULTS:
His Y-BOCS score was reduced from 25 to 4. His depression score and anxiety score were reduced from 19 to 3 and from 12 to 3, respectively. The global assessment of functioning score increased from 32 to 88.CONCLUSIONS:
The remission of the patient suggested that CCT could be an alternative intervention for treatment-refractory OCD and those with severe OCD could be cured in short-term.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Adaptação Psicológica
/
Terapia Cognitivo-Comportamental
/
Transtorno Obsessivo-Compulsivo
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Asian J Psychiatr
Ano de publicação:
2020
Tipo de documento:
Article