Neonatal Weight and Prenatal Exposure to Polychlorinated Biphenyls: A Meta-Analysis.
Asian Pac J Cancer Prev
; 20(11): 3251-3258, 2019 Nov 01.
Article
em En
| MEDLINE
| ID: mdl-31759346
ABSTRACT
BACKGROUND:
This research studied the relationship between maternal exposure to polychlorinated biphenyls and neonatal birth weight through systematic review and meta-analysis of existing literature.METHODS:
We searched for all the studies published in MEDLINE / PUBMEDN / EMBASE (Medical Abstract Database) by June 2018, and seven studies had been selected.RESULTS:
The results showed that there was significant correlation between birth weight reduction and PCBS exposure throughout pregnancy (ß=-0.586g, 95%CI-0.629,-0.543). There was a negative correlation between birth weight and PCBs exposure and umbilical cord serum (ß=-0.833g) and maternal serum (ß= -0.504g).Subgroup analyses showed significantly different effects of PCBs exposure on birth weight in different regions, stages of pregnancy and study designs. It was thought the heterogeneity was mainly caused by geographical regions, stages of pregnancy, and the assessment methods.CONCLUSION:
The meta analysis revealed a negative correlation between PCBs exposure and birth weight but there was significant difference in the correlation between birth weight loss.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Efeitos Tardios da Exposição Pré-Natal
/
Recém-Nascido de Baixo Peso
/
Bifenilos Policlorados
/
Exposição Materna
/
Poluentes Ambientais
Tipo de estudo:
Prognostic_studies
/
Systematic_reviews
Limite:
Female
/
Humans
/
Newborn
/
Pregnancy
Idioma:
En
Revista:
Asian Pac J Cancer Prev
Assunto da revista:
NEOPLASIAS
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
China
País de publicação:
TAILANDIA
/
TAILÂNDIA
/
TH
/
THAILAND