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Dysfunctional missense variant of OAT10/SLC22A13 decreases gout risk and serum uric acid levels.
Higashino, Toshihide; Morimoto, Keito; Nakaoka, Hirofumi; Toyoda, Yu; Kawamura, Yusuke; Shimizu, Seiko; Nakamura, Takahiro; Hosomichi, Kazuyoshi; Nakayama, Akiyoshi; Ooyama, Keiko; Ooyama, Hiroshi; Shimizu, Toru; Ueno, Miki; Ito, Toshimitsu; Tamura, Takashi; Naito, Mariko; Nakashima, Hiroshi; Kawaguchi, Makoto; Takao, Mikiya; Kawai, Yosuke; Osada, Naoki; Ichida, Kimiyoshi; Yamamoto, Ken; Suzuki, Hiroshi; Shinomiya, Nariyoshi; Inoue, Ituro; Takada, Tappei; Matsuo, Hirotaka.
Afiliação
  • Higashino T; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Japan.
  • Morimoto K; Graduate School of Information Science and Technology, Hokkaido University, Sapporo, Japan.
  • Nakaoka H; Department of Pharmacy, The University of Tokyo Hospital, Tokyo, Japan.
  • Toyoda Y; Division of Human Genetics, Department of Integrated Genetics, National Institute of Genetics, Mishima, Japan.
  • Kawamura Y; Department of Pharmacy, The University of Tokyo Hospital, Tokyo, Japan.
  • Shimizu S; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Japan.
  • Nakamura T; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Japan.
  • Hosomichi K; Laboratory for Mathematics, National Defense Medical College, Tokorozawa, Japan.
  • Nakayama A; Department of Bioinformatics and Genomics, Graduate School of Advanced Preventive Medical Sciences, Kanazawa University, Kanazawa, Japan.
  • Ooyama K; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Japan.
  • Ooyama H; Ryougoku East Gate Clinic, Tokyo, Japan.
  • Shimizu T; Ryougoku East Gate Clinic, Tokyo, Japan.
  • Ueno M; Midorigaoka Hospital, Takatsuki, Japan.
  • Ito T; Division of Nursing, National Defense Medical College, Tokorozawa, Japan.
  • Tamura T; Department of Internal Medicine, Self-Defense Forces Central Hospital, Tokyo, Japan.
  • Naito M; Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Nakashima H; Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Kawaguchi M; Department of Preventive Medicine and Public Health, National Defense Medical College, Tokorozawa, Japan.
  • Takao M; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Japan.
  • Kawai Y; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Japan.
  • Osada N; Genome Medical Science Project (Toyama), National Center for Global Health and Medicine, Tokyo, Japan.
  • Ichida K; Graduate School of Information Science and Technology, Hokkaido University, Sapporo, Japan.
  • Yamamoto K; Department of Pathophysiology, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.
  • Suzuki H; Department of Medical Biochemistry, Kurume University School of Medicine, Kurume, Japan.
  • Shinomiya N; Department of Pharmacy, The University of Tokyo Hospital, Tokyo, Japan.
  • Inoue I; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Japan.
  • Takada T; Division of Human Genetics, Department of Integrated Genetics, National Institute of Genetics, Mishima, Japan.
  • Matsuo H; Department of Pharmacy, The University of Tokyo Hospital, Tokyo, Japan hmatsuo@ndmc.ac.jp tappei-tky@umin.ac.jp.
Ann Rheum Dis ; 79(1): 164-166, 2020 01.
Article em En | MEDLINE | ID: mdl-31780526

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transportadores de Ânions Orgânicos / Hiperuricemia / Gota Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Limite: Adult / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Revista: Ann Rheum Dis Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transportadores de Ânions Orgânicos / Hiperuricemia / Gota Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Limite: Adult / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Revista: Ann Rheum Dis Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão País de publicação: Reino Unido